The understanding of the clinical, pathologic and molecular aspects of Alzheimer’s disease and other dementias has advanced rapidly. Brain tissue of demented individuals must be studied for diagnostic and research purposes using a multidisciplinary approach. The Indiana Alzheimer Disease Center Clinical Core at IU School of Medicine has collected a wealth of information through clinical assessments, cognitive testing, imaging, and the collection of biomarkers. Linking this clinical data with autopsy findings maximizes the impact of information collected and is invaluable in supporting future research.
Specifically, information obtained from examinations of donated tissue helps Indiana Alzheimer Disease Center researchers identify genetic causes of Alzheimer’s disease and environmental risk factors of Alzheimer’s disease, and advances development of technology in the early diagnosis and treatment of Alzheimer’s disease. The data is used in studies conducted at IU School of Medicine, and the information is entered into a national databank, where it can be accessed by researchers around the world. The identity of Indiana Alzheimer Disease Center subjects is kept strictly confidential.