The Clinical Core supports the overall mission of Indiana University School of Medicine to improve early detection of neurodegenerative diseases at the transition from normal cognition to prodromal stages by providing researchers with high quality clinical, imaging, biomarker and neuropathological data in Alzheimer’s disease and hereditary dementias.
The Clinical Core recruits and longitudinally follows a diverse cohort of subjects and collects standardized clinical, neuropsychological and biomarker data to support innovative interdisciplinary research locally, nationally and internationally. Critical to the function of the Indiana Alzheimer’s Disease Research Center, this core identifies and clinically characterizes patients in the presymptomatic and prodromal stages of dementia, including those with MCI, Alzheimer’s disease, non- Alzheimer’s disease and mixed dementia. The core also advances data on healthy controls.
In furtherance of the center’s overarching goal of supporting the broader dementia research endeavor, the Clinical Core shares resources and data and collaborates regionally, nationally and internationally with other Alzheimer’s disease centers and the NACC as well as ADGC, ADNI, DIAN, NCRAD, the ADCS, the Alzheimer’s Association research programs, and participates in innovative industry-sponsored investigational new drug trials.