The Endocrine Scientist Training Program at IU School of Medicine is an NIH-funded program that prepares pediatric endocrinology and combined medicine-pediatric endocrinology fellows for a career in clinical or basic science research. This program is completed during the second or third year of fellowship training and consists of mentor-based training in clinical or laboratory research techniques as well as didactic courses in clinical research methods or molecular biologic techniques, research ethics and statistics.
This program consists of two tracks: the Endocrinology Clinical Research Track and the Basic Science of Endocrinology Track. Fellows following the Endocrinology Clinical Research Track obtain a Master of Clinical Research degree at the completion of their three-year fellowship.
During the first months of training, Endocrine Scientist Training Program fellows meet with the program directors to explore their interests. The directors review potential areas for research and discuss potential mentors. At the end of the first six months of training, fellows will have identified both a research mentor and a research focus and be actively involved in research activities that continue through the duration of their training. Fellows have the opportunity to present findings at national meetings upon the completion of their first year. Additional opportunities exist for authoring case reports, review articles and book chapters.
Clinical Research Track
Working with faculty mentors, fellows conduct original clinical research and advance research already underway. Fellows have the opportunity to simultaneously complete a master’s degree in clinical or translational research, with coursework including clinical research methods, clinical trials, research communications, biostatistics and research ethics. Areas of clinical research within the division include long term outcomes of central precocious puberty, osteogenesis imperfecta, hypophosphatasia, immunomodulatory therapies to prevent or modify type 1 diabetes, treatment of type 2 diabetes, and the relationship of sleep apnea to insulin resistance and obesity.
Basic Science Track
Many fellows pursuing basic science research receive training in the Wells Center for Pediatric Research with the diabetes research team, although fellows may elect to train in labs in other pediatrics divisions or other departments. Diabetes researchers at IU School of Medicine are committed to understanding the biology and molecular mechanisms that lead to the development of both type 1 and type 2 diabetes in children and cultivate research that speeds the discovery of more effective therapies. Areas of laboratory based research include work on pancreatic islets, islet transplantation, pathophysiology of diabetes, molecular pathways, insulin-producing cells, stem cell therapies and targeted therapies.