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Clinical Pharmacology Fellows Publications

Mohammad Yaseen Abbasi, PhD

No current publications


Lauren A. Bell, MD, MPH*

Adams ZW, Agley J, Pederson CA, Bell LA, Aalsma MC, Jackson T, Grant MT, Ott CA, Hulvershorn LA. Use of Project ECHO to promote evidence based care for justice involved adults with opioid use disorder. Subst Abus. 2022;43(1):336-343. doi: 10.1080/08897077.2021.1941518. Epub 2021 Jul 20. PMID: 34283701; PMCID: PMC8889500.

Oliver AP, Bell LA, Agley J, Bixler K, Hulvershorn LA, Adams ZW. Examining the Efficacy of Project ECHO to Improve Clinicians' Knowledge and Preparedness to Treat Adolescent Vaping. Clin Pediatr (Phila). 2022 Jun 30:99228221107816. doi: 10.1177/00099228221107816. Epub ahead of print. PMID: 35774009.

Debora Gisch, PhD

Melo Ferreira R, Gisch DL, Eadon MT. Spatial transcriptomics and the kidney. Curr Opin Nephrol Hypertens. 2022 May 1;31(3):244-250. doi: 10.1097/MNH.0000000000000781. Epub 2022 Feb 3. PMID: 35125393; PMCID: PMC9035033.

Avin KG, Hughes MC, Chen NX, Srinivasan S, O'Neill KD, Evan AP, Bacallao RL, Schulte ML, Moorthi RN, Gisch DL, Perry CGR, Moe SM, O'Connell TM. Skeletal muscle metabolic responses to physical activity are muscle type specific in a rat model of chronic kidney disease. Sci Rep. 2021 May 7;11(1):9788. doi: 10.1038/s41598-021-89120-8. PMID: 33963215; PMCID: PMC8105324.


Chetna Jadala, PhD

No current publications


Yan Jin, MD, MS*
Shi X, Xi B, Jasbi P, Turner C, Jin Y, Gu H. Comprehensive Isotopic Targeted Mass Spectrometry: Reliable Metabolic Flux Analysis with Broad Coverage. Anal Chem. 2020;92(17):11728-11738. doi:10.1021/acs.analchem.0c01767
 
Guo Y, Farmen MW, Jin Y, et al. Deciphering ADME genetic data using an automated haplotype approach. Pharmacogenet Genomics. 2014;24(6):292-305. doi:10.1097/FPC.0000000000000047
 
Jin Y, Regev A, Kam J, et al. Dose-dependent acute liver injury with hypersensitivity features in humans due to a novel microsomal prostaglandin E synthase 1 inhibitor. Br J Clin Pharmacol. 2018;84(1):179-188. doi:10.1111/bcp.13423
 
Jin Y, Smith C, Hu L, et al. LY3127760, a Selective Prostaglandin E4 (EP4) Receptor Antagonist, and Celecoxib: A Comparison of Pharmacological Profiles. Clin Transl Sci. 2018;11(1):46-53. doi:10.1111/cts.12497
 
Kreutz RP, Nystrom P, Kreutz Y, et al. Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response. Clin Pharmacol. 2012;4:13-20. doi:10.2147/CPAA.S27822
 
Duke JD, Han X, Wang Z, et al. Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions. PLoS Comput Biol. 2012;8(8):e1002614. doi:10.1371/journal.pcbi.1002614
 
Kreutz RP, Bitar A, Owens J, et al. Factor XIII Val34Leu polymorphism and recurrent myocardial infarction in patients with coronary artery disease. J Thromb Thrombolysis. 2014;38(3):380-387. doi:10.1007/s11239-014-1059-4
 
Kreutz RP, Owens J, Jin Y, et al. Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response. Clin Pharmacol. 2013;5:185-192. Published 2013 Dec 9. doi:10.2147/CPAA.S53151
 
Carpenter JS, Yu M, Wu J, et al. Evaluating the role of serotonin in hot flashes after breast cancer using acute tryptophan depletion. Menopause. 2009;16(4):644-652. doi:10.1097/gme.0b013e318199e9f6
 
Borges S, Desta Z, Jin Y, et al. Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients [published correction appears in J Clin Pharmacol. 2010 Jun;50(6):725. Philip, Santosh [corrected to Philips, Sanosh]]. J Clin Pharmacol. 2010;50(4):450-458. doi:10.1177/0091270009359182
 
Jin Y, Hayes DF, Li L, et al. Estrogen receptor genotypes influence hot flash prevalence and composite score before and after tamoxifen therapy. J Clin Oncol. 2008;26(36):5849-5854. doi:10.1200/JCO.2008.16.8377
 
Jin Y, Desta Z, Stearns V, et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst. 2005;97(1):30-39. doi:10.1093/jnci/dji005
 
Kreutz RP, Nystrom P, Kreutz Y, et al. Inhibition of platelet aggregation by prostaglandin E1 (PGE1) in diabetic patients during therapy with clopidogrel and aspirin. Platelets. 2013;24(2):145-150. doi:10.3109/09537104.2012.661107
 
Borges S, Desta Z, Li L, et al. Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment. Clin Pharmacol Ther. 2006;80(1):61-74. doi:10.1016/j.clpt.2006.03.013


Murugesh Kandasamy, PhD

No current publications


Srikar Malireddy, MD*
Quinney SK, Malireddy SR, Vuppalanchi R, Hamman MA, Chalasani N, Gorski JC, Hall SD. Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin. Eur J Clin Pharmacol. 2013 Mar;69(3):439-48. doi: 10.1007/s00228-012-1339-x. Epub 2012 Jul 10. PMID: 22777148; PMCID: PMC3712509.
 
Chiorean EG, Malireddy S, Younger AE, Jones DR, Waddell MJ, Sloop MI, Yu M, Hall SD, Schneider B, Sweeney CJ. A phase I dose escalation and pharmacokinetic study of vatalanib (PTK787/ZK 222584) in combination with paclitaxel in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2010 Aug;66(3):441-8. doi: 10.1007/s00280-009-1179-2. Epub 2009 Nov 29. PMID: 20091169.
 
Malireddy SR, Pinto AG, Chalasani NP, Gorski JC, Hall SD. Altered first-pass effects in a liver transplant recipient explained intraindividual variation in calcineurin inhibitor concentrations: a case report. Transplant Proc. 2008 Jun;40(5):1789-91. doi: 10.1016/j.transproceed.2008.02.073. PMID: 18589198.

Tarun Mapder, PharmD*
Browning AP, Sharp JA, Mapder T, Baker CM, Burrage K, Simpson MJ. Persistence as an Optimal Hedging Strategy. Biophys J. 2021 Jan 5;120(1):133-142. doi: 10.1016/j.bpj.2020.11.2260. Epub 2020 Nov 28. PMID: 33253635; PMCID: PMC7820789.
 
Roy C, Mandal SM, Mondal SK, Mukherjee S, Mapder T, Ghosh W, Chakraborty R. Trends of mutation accumulation across global SARS-CoV-2 genomes: Implications for the evolution of the novel coronavirus. Genomics. 2020 Nov;112(6):5331-5342. doi: 10.1016/j.ygeno.2020.11.003. Epub 2020 Nov 5. PMID: 33161087; PMCID: PMC7644180.
 
Ferrari Gianlupi J, Mapder T, Sego TJ, Sluka JP, Quinney SK, Craig M, Stratford RE Jr, Glazier JA. Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2. Viruses. 2022 Mar 14;14(3):605. doi: 10.3390/v14030605. PMID: 35337012; PMCID: PMC8953050.

Smith Marri, MD*
Neuschwander-Tetri BA, Loomba R, Sanyal AJ, Lavine JE, Van Natta ML, Abdelmalek MF, Chalasani N, Dasarathy S, Diehl AM, Hameed B, Kowdley KV, McCullough A, Terrault N, Clark JM, Tonascia J, Brunt EM, Kleiner DE, Doo E; NASH Clinical Research Network. Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial. Lancet. 2015 Mar 14;385(9972):956-65. doi: 10.1016/S0140-6736(14)61933-4. Epub 2014 Nov 7. Erratum in: Lancet. 2015 Mar 14;385(9972):946. Erratum in: Lancet. 2016 Apr 16;387(10028):1618. PMID: 25468160; PMCID: PMC4447192.
 
Mohamed S, Johnson GR, Chen P, Hicks PB, Davis LL, Yoon J, Gleason TC, Vertrees JE, Weingart K, Tal I, Scrymgeour A, Lawrence DD, Planeta B, Thase ME, Huang GD, Zisook S; and the VAST-D Investigators, Rao SD, Pilkinton PD, Wilcox JA, Iranmanesh A, Sapra M, Jurjus G, Michalets JP, Aslam M, Beresford T, Anderson KD, Fernando R, Ramaswamy S, Kasckow J, Westermeyer J, Yoon G, D'Souza DC, Larson G, Anderson WG, Klatt M, Fareed A, Thompson SI, Carrera CJ, Williams SS, Juergens TM, Albers LJ, Nasdahl CS, Villarreal G, Winston JL, Nogues CA, Connolly KR, Tapp A, Jones KA, Khatkhate G, Marri S, Suppes T, LaMotte J, Hurley R, Mayeda AR, Niculescu AB 3rd, Fischer BA, Loreck DJ, Rosenlicht N, Lieske S, Finkel MS, Little JT. Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial. JAMA. 2017 Jul 11;318(2):132-145. doi: 10.1001/jama.2017.8036. PMID: 28697253; PMCID: PMC5817471.
 
Vuppalanchi R, Marri S, Kolwankar D, Considine RV, Chalasani N. Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study. J Clin Gastroenterol. 2005 Mar;39(3):237-42. doi: 10.1097/01.mcg.0000152747.79773.2f. PMID: 15718867.

Emily Mason, PhD
Mason ER, Wu F, Patel RR, Xiao Y, Cannon SC, Cummins TR. Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations. eNeuro. 2019 Oct 16;6(5):ENEURO.0141-19.2019. doi: 10.1523/ENEURO.0141-19.2019. PMID: 31558572; PMCID: PMC6795554.
 
Mason ER, Cummins TR. Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967. Int J Mol Sci. 2020 Apr 1;21(7):2454. doi: 10.3390/ijms21072454. PMID: 32244818; PMCID: PMC7177867.
 
Potjewyd FM, Annor-Gyamfi JK, Aubé J, Chu S, Conlon IL, Frankowski KJ, Guduru SKR, Hardy BP, Hopkins MD, Kinoshita C, Kireev DB, Mason ER, Moerk CT, Nwogbo F, Pearce KH Jr, Richardson TI, Rogers DA, Soni DM, Stashko M, Wang X, Wells C, Willson TM, Frye SV, Young JE, Axtman AD. Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology. Alzheimers Dement (N Y). 2022 Apr 12;8(1):e12253. doi: 10.1002/trc2.12253. PMID: 35434254; PMCID: PMC9005681.
 
Potjewyd FM, Annor-Gyamfi JK, Aubé J, Chu S, Conlon IL, Frankowski KJ, Guduru SKR, Hardy BP, Hopkins MD, Kinoshita C, Kireev DB, Mason ER, Moerk CT, Nwogbo F, Pearce KH, Richardson TI, Rogers DA, Soni DM, Stashko M, Wang X, Wells C, Willson TM, Frye SV, Young JE, Axtman AD. AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery. Alzheimers Dement (N Y). 2022 Apr 20;8(1):e12246. doi: 10.1002/trc2.12246. PMID: 35475262; PMCID: PMC9019904.

Darius Meiman, PharmD*
McNamara PJ, Meiman D. Predicting Drug Binding to Human Serum Albumin and Alpha One Acid Glycoprotein in Diseased and Age Patient Populations. J Pharm Sci. 2019 Aug;108(8):2737-2747. doi: 10.1016/j.xphs.2019.03.018. Epub 2019 Mar 21. PMID: 30905706.
 

Ricardo Melo Ferreira, PhD
Melo Ferreira R, Sabo AR, Winfree S, Collins KS, Janosevic D, Gulbronson CJ, Cheng YH, Casbon L, Barwinska D, Ferkowicz MJ, Xuei X, Zhang C, Dunn KW, Kelly KJ, Sutton TA, Hato T, Dagher PC, El-Achkar TM, Eadon MT. Integration of spatial and single-cell transcriptomics localizes epithelial cell-immune cross-talk in kidney injury. JCI Insight. 2021 Jun 22;6(12):e147703. doi: 10.1172/jci.insight.147703. PMID: 34003797; PMCID: PMC8262485.
 
Janosevic D, Myslinski J, McCarthy TW, Zollman A, Syed F, Xuei X, Gao H, Liu YL, Collins KS, Cheng YH, Winfree S, El-Achkar TM, Maier B, Melo Ferreira R, Eadon MT, Hato T, Dagher PC. The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline. Elife. 2021 Jan 15;10:e62270. doi: 10.7554/eLife.62270. PMID: 33448928; PMCID: PMC7810465.
 
Melo Ferreira R, Gisch DL, Eadon MT. Spatial transcriptomics and the kidney. Curr Opin Nephrol Hypertens. 2022 May 1;31(3):244-250. doi: 10.1097/MNH.0000000000000781. Epub 2022 Feb 3. PMID: 35125393; PMCID: PMC9035033.
 
Eadon MT, Lampe S, Baig MM, Collins KS, Melo Ferreira R, Mang H, Cheng YH, Barwinska D, El-Achkar TM, Schwantes-An TH, Winfree S, Temm CJ, Ferkowicz MJ, Dunn KW, Kelly KJ, Sutton TA, Moe SM, Moorthi RN, Phillips CL, Dagher PC; Kidney Precision Medicine Project. Clinical, histopathologic and molecular features of idiopathic and diabetic nodular mesangial sclerosis in humans. Nephrol Dial Transplant. 2021 Dec 31;37(1):72-84. doi: 10.1093/ndt/gfaa331. PMID: 33537765; PMCID: PMC8826640.
 
Melo Ferreira R, Freije BJ, Eadon MT. Deconvolution Tactics and Normalization in Renal Spatial Transcriptomics. Front Physiol. 2022 Jan 13;12:812947. doi: 10.3389/fphys.2021.812947. PMID: 35095570; PMCID: PMC8793484.
 
Barwinska D, El-Achkar TM, Melo Ferreira R, Syed F, Cheng YH, Winfree S, Ferkowicz MJ, Hato T, Collins KS, Dunn KW, Kelly KJ, Sutton TA, Rovin BH, Parikh SV, Phillips CL, Dagher PC, Eadon MT; Kidney Precision Medicine Project. Molecular characterization of the human kidney interstitium in health and disease. Sci Adv. 2021 Feb 10;7(7):eabd3359. doi: 10.1126/sciadv.abd3359. PMID: 33568476; PMCID: PMC7875540.
 
Collins KS, Eadon MT, Cheng YH, Barwinska D, Melo Ferreira R, McCarthy TW, Janosevic D, Syed F, Maier B, El-Achkar TM, Kelly KJ, Phillips CL, Hato T, Sutton TA, Dagher PC. Alterations in Protein Translation and Carboxylic Acid Catabolic Processes in Diabetic Kidney Disease. Cells. 2022 Mar 30;11(7):1166. doi: 10.3390/cells11071166. PMID: 35406730; PMCID: PMC8997785.

Nick Miles, PharmD*
Tillman EM, Suppes SL, Miles N, Duty AM, Kelley KL, Goldman JL. Risks and mitigation strategies to prevent etoposide infusion-related reactions in children. Pharmacotherapy. 2021 Aug;41(8):700-706. doi: 10.1002/phar.2603. Epub 2021 Jun 29. PMID: 34129705; PMCID: PMC8617599.
 
Lamb BK, Cambaliza MO, Davis KJ, Edburg SL, Ferrara TW, Floerchinger C, Heimburger AM, Herndon S, Lauvaux T, Lavoie T, Lyon DR, Miles N, Prasad KR, Richardson S, Roscioli JR, Salmon OE, Shepson PB, Stirm BH, Whetstone J. Direct and Indirect Measurements and Modeling of Methane Emissions in Indianapolis, Indiana. Environ Sci Technol. 2016 Aug 16;50(16):8910-7. doi: 10.1021/acs.est.6b01198. Epub 2016 Aug 3. PMID: 27487422.

Aislinn O'Kane, PharmD*

No current publications


Chimnonso Onuoha, PharmD*
Onuoha CP, Ipe J, Simpson E, Liu Y, Skaar TC, Kreutz RP. MicroRNA sequencing in patients with coronary artery disease - considerations for use as biomarker for thrombotic risk. Clin Transl Sci. 2022 May 29. doi: 10.1111/cts.13307. Epub ahead of print. PMID: 35643946.

Rebecca Pierson, MD*
Pierson RC, Scott NP, Briscoe KE, Haas DM. A review of post-caesarean infectious morbidity: how to prevent and treat. J Obstet Gynaecol. 2018 Jul;38(5):591-597. doi: 10.1080/01443615.2017.1394281. Epub 2018 Feb 12. PMID: 29433350.
 
Eadon MT, Desta Z, Levy KD, Decker BS, Pierson RC, Pratt VM, Callaghan JT, Rosenman MB, Carpenter JS, Holmes AM, McDonald CA, Benson EA, Patil AS, Vuppalanchi R, Gufford BT, Dave N, Robarge JD, Hyder MA, Haas DM, Kreutz RP, Dexter PR, Skaar TC, Flockhart DA. Implementation of a pharmacogenomics consult service to support the INGENIOUS trial. Clin Pharmacol Ther. 2016 Jul;100(1):63-6. doi: 10.1002/cpt.347. Epub 2016 Mar 31. PMID: 26850569; PMCID: PMC4899152.
 
Pierson RC, Gufford BT, Desta Z, Eadon MT. Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial. Pharmacogenomics. 2017 Jun;18(9):835-841. doi: 10.2217/pgs-2017-0042. Epub 2017 Jun 8. PMID: 28594278; PMCID: PMC5591461.
 
Pierson RC, Gordon SS, Haas DM. A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. Obstet Gynecol. 2014 Sep;124(3):515-519. doi: 10.1097/AOG.0000000000000426. PMID: 25162251; PMCID: PMC4147675.
 
Dorr ML, Pierson RC, Daggy J, Quinney SK, Haas DM. Buccal versus Vaginal Misoprostol for Term Induction of Labor: A Retrospective Cohort Study. Am J Perinatol. 2019 Jun;36(7):765-772. doi: 10.1055/s-0038-1675219. Epub 2018 Oct 31. PMID: 30380580; PMCID: PMC7692025.
 
Haas DM, Daggy J, Flannery KM, Dorr ML, Bonsack C, Bhamidipalli SS, Pierson RC, Lathrop A, Towns R, Ngo N, Head A, Morgan S, Quinney SK. A comparison of vaginal versus buccal misoprostol for cervical ripening in women for labor induction at term (the IMPROVE trial): a triple-masked randomized controlled trial. Am J Obstet Gynecol. 2019 Sep;221(3):259.e1-259.e16. doi: 10.1016/j.ajog.2019.04.037. Epub 2019 May 7. PMID: 31075246; PMCID: PMC7692024.
 
Pierson RC, Johnson BE, Voirol JR, Kasper KM. Utility of Endocervical Sampling at Time of Colposcopy when Referral Cytology Is Low Grade or Better. Reprod Sci. 2020 Jan;27(1):55-60. doi: 10.1007/s43032-019-00135-z. Epub 2020 Jan 1. PMID: 32046412.
 
Towns R, Quinney SK, Pierson RC, Haas DM. Survey of Provider Preferences Regarding the Route of Misoprostol for Induction of Labor at Term. AJP Rep. 2017 Jul;7(3):e158-e162. doi: 10.1055/s-0037-1603954. Epub 2017 Jul 25. PMID: 28752015; PMCID: PMC5526707.
 
Pierson RC, Malone AM, Haas DM. Increasing Influenza Vaccination Rates in a Busy Urban Clinic. J Nat Sci. 2015;1(3):e57. PMID: 25750936; PMCID: PMC4347981.
 
Vorontsova Y, Haas DM, Flannery K, Masters AR, Silva LL, Pierson RC, Yeley B, Hogg G, Guise D, Heathman M, Quinney SK. Pharmacokinetics of vaginal versus buccal misoprostol for labor induction at term. Clin Transl Sci. 2022 May 19. doi: 10.1111/cts.13306. Epub ahead of print. PMID: 35587540.

Nick Powell, PharmD*
Powell NR, Zhao H, Ipe J, Liu Y, Skaar TC. Mapping the miRNA-mRNA Interactome in Human Hepatocytes and Identification of Functional mirSNPs in Pharmacogenes. Clin Pharmacol Ther. 2021 Oct;110(4):1106-1118. doi: 10.1002/cpt.2379. Epub 2021 Aug 13. PMID: 34314509; PMCID: PMC9007393.
 
Powell NR, Shugg T, Ly RC, Albany C, Radovich M, Schneider BP, Skaar TC. Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report. Front Oncol. 2022 Jan 31;11:809527. doi: 10.3389/fonc.2021.809527. PMID: 35174070; PMCID: PMC8841796.

Troy Quigg, MD*
Pulsipher MA, Logan BR, Kiefer DM, Chitphakdithai P, Riches ML, Rizzo JD, Anderlini P, Leitman SF, Varni JW, Kobusingye H, Besser RM, Miller JP, Drexler RJ, Abdel-Mageed A, Ahmed IA, Ball ED, Bolwell BJ, Bunin NJ, Cheerva A, Delgado DC, Dvorak CC, Gillio AP, Hahn TE, Hale GA, Haight AE, Hayes-Lattin BM, Kasow KA, Linenberger M, Magalhaes-Silverman M, Mori S, Prasad VK, Quigg TC, Sahdev I, Schriber JR, Shenoy S, Tse WT, Yanik GA, Navarro WH, Horowitz MM, Confer DL, Shaw BE, Switzer GE. Higher Risks of Toxicity and Incomplete Recovery in 13- to 17-Year-Old Females after Marrow Donation: RDSafe Peds Results. Biol Blood Marrow Transplant. 2019 May;25(5):955-964. doi: 10.1016/j.bbmt.2018.12.765. Epub 2018 Dec 31. PMID: 30605731; PMCID: PMC6511296.
 
Metzger IF, Quigg TC, Epstein N, Aregbe AO, Thong N, Callaghan JT, Flockhart DA, Nguyen AT, Stevens CK, Gupta SK, Desta Z. Substantial effect of efavirenz monotherapy on bilirubin levels in healthy volunteers. Curr Ther Res Clin Exp. 2014 Sep 27;76:64-9. doi: 10.1016/j.curtheres.2014.05.002. PMID: 25352936; PMCID: PMC4209507.
 
Michaud V, Ogburn E, Thong N, Aregbe AO, Quigg TC, Flockhart DA, Desta Z. Induction of CYP2C19 and CYP3A activity following repeated administration of efavirenz in healthy volunteers. Clin Pharmacol Ther. 2012 Mar;91(3):475-82. doi: 10.1038/clpt.2011.249. Epub 2012 Feb 8. PMID: 22318618; PMCID: PMC3667659.
 
Quigg TC, Mahajerin A, Sullivan PD, Pradhan K, Bauer NS. Ages and Stages Questionnaires-3 developmental screening of infants and young children with cancer. J Pediatr Oncol Nurs. 2013 Sep-Oct;30(5):235-41. doi: 10.1177/1043454213493510. Epub 2013 Jul 18. PMID: 23867965; PMCID: PMC4026287.
 
Quigg TC, Kim YJ, Goebel WS, Haut PR. Lung function before and after pediatric allogeneic hematopoietic stem cell transplantation: a predictive role for DLCOa/VA. J Pediatr Hematol Oncol. 2012 May;34(4):304-9. doi: 10.1097/MPH.0b013e3182346ed8. PMID: 22246156; PMCID: PMC4019990.
 
Jacobsohn DA, Loken MR, Fei M, Adams A, Brodersen LE, Logan BR, Ahn KW, Shaw BE, Kletzel M, Olszewski M, Khan S, Meshinchi S, Keating A, Harris A, Teira P, Duerst RE, Margossian SP, Martin PL, Petrovic A, Dvorak CC, Nemecek ER, Boyer MW, Chen AR, Davis JH, Shenoy S, Savasan S, Hudspeth MP, Adams RH, Lewis VA, Kheradpour A, Kasow KA, Gillio AP, Haight AE, Bhatia M, Bambach BJ, Haines HL, Quigg TC, Greiner RJ, Talano JM, Delgado DC, Cheerva A, Gowda M, Ahuja S, Ozkaynak M, Mitchell D, Schultz KR, Fry TJ, Loeb DM, Pulsipher MA. Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression. Biol Blood Marrow Transplant. 2018 Oct;24(10):2040-2046. doi: 10.1016/j.bbmt.2018.06.010. Epub 2018 Jun 19. PMID: 29933069; PMCID: PMC6239928.
 
Quigg TC, Haddad NG, Buchsbaum JC, Shih CS. Hypothalamic obesity syndrome: rare presentation of CNS+ B-cell lymphoblastic lymphoma. Pediatr Blood Cancer. 2012 Nov;59(5):930-3. doi: 10.1002/pbc.24058. Epub 2011 Dec 27. PMID: 22213612; PMCID: PMC4020003.

Sara Quinney, PharmD, PhD*

Shanks AL, Grasch JL, Quinney SK, Haas DM. Controversies in antenatal corticosteroids. Semin Fetal Neonatal Med. 2019 Jun;24(3):182-188. doi: 10.1016/j.siny.2019.05.002. Epub 2019 May 29. PMID: 31155465 Review.

Quinney SK, Bonate PL. A pharmacometrician's role in enhancing medication use in pregnancy and lactation. J Pharmacokinet Pharmacodyn. 2020 Aug;47(4):267-269. doi: 10.1007/s10928-020-09707-y. PMID: 32803462 Free PMC article. No abstract available.

Aruldhas BW, Quinney SK, Overholser BR, Heathman MA, Masters AR, Ly RC, Gao H, Packiasabapathy S, Sadhasivam S. Pharmacokinetic modeling of R and S-Methadone and their metabolites to study the effects of various covariates in post-operative children. CPT Pharmacometrics Syst Pharmacol. 2021 Oct;10(10):1183-1194. doi: 10.1002/psp4.12687. Epub 2021 Aug 26. PMID: 34435753 Free PMC article.

Packiasabapathy S, Aruldhas BW, Horn N, Overholser BR, Quinney SK, Renschler JS, Sadhasivam S. Pharmacogenomics of methadone: a narrative review of the literature. Pharmacogenomics. 2020 Aug;21(12):871-887. doi: 10.2217/pgs-2020-0040. Epub 2020 Jul 24. PMID: 32705966 Free PMC article. Review.

Wu HY, Shendre A, Zhang S, Zhang P, Wang L, Zeruesenay D, Rocha LM, Shatkay H, Quinney SK, Ning X, Li L. Translational Knowledge Discovery Between Drug Interactions and Pharmacogenetics. Clin Pharmacol Ther. 2020 Apr;107(4):886-902. doi: 10.1002/cpt.1745. Epub 2020 Feb 3. PMID: 31863452 Free PMC article. Review.

Liao MZ, Flood Nichols SK, Ahmed M, Clark S, Hankins GD, Caritis S, Venkataramanan R, Haas D, Quinney SK, Haneline LS, Tita AT, Manuck T, Wang J, Thummel KE, Brown LM, Ren Z, Easterling TR, Hebert MF. Effects of Pregnancy on the Pharmacokinetics of Metformin. Drug Metab Dispos. 2020 Apr;48(4):264-271. doi: 10.1124/dmd.119.088435. Epub 2020 Jan 24. PMID: 31980499 Free PMC article. Clinical Trial.

Quinney SK, Gullapelli R, Haas DM. Translational Systems Pharmacology Studies in Pregnant Women. CPT Pharmacometrics Syst Pharmacol. 2018 Feb;7(2):69-81. doi: 10.1002/psp4.12269. Epub 2017 Dec 14. PMID: 29239132 Free PMC article. Review.

Metzger IF, Thomas AE, Evrard CA, Jones DR, Masters AR, Haas DM, Haneline LS, Quinney SK. Stereoselective Analysis of Methadone and EDDP in Laboring Women and Neonates in Plasma and Dried Blood Spots and Association with Neonatal Abstinence Syndrome. Am J Perinatol. 2021 Jul;38(9):968-975. doi: 10.1055/s-0040-1701505. Epub 2020 Feb 12. PMID: 32052397

Quinney SK, Patil AS, Flockhart DA. Is personalized medicine achievable in obstetrics? Semin Perinatol. 2014 Dec;38(8):534-40. doi: 10.1053/j.semperi.2014.08.017. Epub 2014 Oct 3. PMID: 25282474 Free PMC article. Review.

Sorkin BC, Kuszak AJ, Bloss G, Fukagawa NK, Hoffman FA, Jafari M, Barrett B, Brown PN, Bushman FD, Casper SJ, Chilton FH, Coffey CS, Ferruzzi MG, Hopp DC, Kiely M, Lakens D, MacMillan JB, Meltzer DO, Pahor M, Paul J, Pritchett-Corning K, Quinney SK, Rehermann B, Setchell KDR, Sipes NS, Stephens JM, Taylor DL, Tiriac H, Walters MA, Xi D, Zappalá G, Pauli GF. Improving natural product research translation: From source to clinical trial. FASEB J. 2020 Jan;34(1):41-65. doi: 10.1096/fj.201902143R. Epub 2019 Dec 10. PMID: 31914647 Free PMC article.

Marks C, Silvola R, Teal E, Quinney SK, Haas DM. Comparing newborn outcomes after prenatal exposure to individual antidepressants: A retrospective cohort study. Pharmacotherapy. 2021 Nov;41(11):907-914. doi: 10.1002/phar.2628. Epub 2021 Oct 26. PMID: 34587291

Sukoff Rizzo SJ, Masters A, Onos KD, Quinney S, Sasner M, Oblak A, Lamb BT, Territo PR; MODEL‐AD consortium. Improving preclinical to clinical translation in Alzheimer's disease research. Alzheimers Dement (N Y). 2020 Jun 14;6(1):e12038. doi: 10.1002/trc2.12038. eCollection 2020. PMID: 32548237 Free PMC article.

McKinzie AH, Yang Z, Teal E, Daggy JK, Tepper RS, Quinney SK, Rhoads E, Haneline LS, Haas DM. Are newborn outcomes different for term babies who were exposed to antenatal corticosteroids? Am J Obstet Gynecol. 2021 Nov;225(5):536.e1-536.e7. doi: 10.1016/j.ajog.2021.04.251. Epub 2021 May 3. PMID: 33957112

Yao X, Tsang T, Sun Q, Quinney S, Zhang P, Ning X, Li L, Shen L. Mining and visualizing high-order directional drug interaction effects using the FAERS database. BMC Med Inform Decis Mak. 2020 Mar 18;20(Suppl 2):50. doi: 10.1186/s12911-020-1053-z. PMID: 32183790 Free PMC article.

Packiasabapathy S, Aruldhas BW, Zhang P, Overholser BR, Quinney SK, Sadhasivam S. Novel associations between CYP2B6 polymorphisms, perioperative methadone metabolism and clinical outcomes in children. Pharmacogenomics. 2021 Jul;22(10):591-602. doi: 10.2217/pgs-2021-0039. Epub 2021 Jun 8. PMID: 34100292 Free PMC article.

Zhang P, Wu HY, Chiang CW, Wang L, Binkheder S, Wang X, Zeng D, Quinney SK, Li L. Translational Biomedical Informatics and Pharmacometrics Approaches in the Drug Interactions Research. CPT Pharmacometrics Syst Pharmacol. 2018 Feb;7(2):90-102. doi: 10.1002/psp4.12267. Epub 2018 Jan 9. PMID: 29193890 Free PMC article. Review.

Quinney SK, Benjamin T, Zheng X, Patil AS. Characterization of Maternal and Fetal CYP3A-Mediated Progesterone Metabolism. Fetal Pediatr Pathol. 2017 Oct;36(5):400-411. doi:10.1080/15513815.2017.1354411. Epub 2017 Sep 26.PMID: 28949811 Free PMC article.

Kinney MT, Quinney SK, Trussell HK, Silva LL, Ibrahim SA, Haas DM. Do maternal demographics and prenatal history impact the efficacy of betamethasone therapy for threatened preterm labor? BMC Pregnancy Childbirth. 2021 Jun 24;21(1):442. doi: 10.1186/s12884-021-03949-5. PMID: 34167497 Free PMC article.

Sadhasivam S, Aruldhas BW, Packiasabapathy S, Overholser BR, Zhang P, Zang Y, Renschler JS, Fitzgerald RE, Quinney SK. A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects. Anesth Analg. 2021 Aug 1;133(2):327-337. doi:10.1213/ANE.0000000000005366.PMID: 33481403 Free PMC article. Clinical Trial.

Caan BJ, Meyerhardt JA, Brown JC, Campbell KL, Cespedes Feliciano EM, Lee C, Ross MC, Quinney S, Quesenberry C, Sternfeld B, Schmitz KH. Recruitment strategies and design considerations in a trial of resistance training to prevent dose-limiting toxicities in colon cancer patients undergoing chemotherapy. Contemp Clin Trials. 2021 Feb;101:106242. doi: 10.1016/j.cct.2020.106242. Epub 2020 Dec 7. PMID: 33301991 Free PMC article. Clinical Trial.

Shuster DL, Shireman LM, Ma X, Shen DD, Flood Nichols SK, Ahmed MS, Clark S, Caritis S, Venkataramanan R, Haas DM, Quinney SK, Haneline LS, Tita AT, Manuck TA, Thummel KE, Brown LM, Ren Z, Brown Z, Easterling TR, Hebert MF. Pharmacodynamics of Glyburide, Metformin, and Glyburide/Metformin Combination Therapy in the Treatment of Gestational Diabetes Mellitus.Clin Pharmacol Ther. 2020 Jun;107(6):1362-1372. doi: 10.1002/cpt.1749. Epub 2020 Jan 25.PMID: 31869430 Free PMC article. Clinical Trial.

Haas DM, Benjamin T, Sawyer R, Quinney SK. Short-term tocolytics for preterm delivery - current perspectives.Int J Womens Health. 2014 Mar 27;6:343-9. doi: 10.2147/IJWH.S44048. eCollection 2014. PMID: 24707187 Free PMC article. Review.

Hua L, Chiang CW, Cong W, Li J, Wang X, Cheng L, Feng W, Quinney SK, Wang L, Li L. The Cancer Drug Fraction of Metabolism Database. CPT Pharmacometrics Syst Pharmacol. 2019 Jul;8(7):511-519. doi: 10.1002/psp4.12417. Epub 2019 Jun 17. PMID: 31206254 Free PMC article.

Wang X, Zhang P, Chiang CW, Wu H, Shen L, Ning X, Zeng D, Wang L, Quinney SK, Feng W, Li L. Mixture drug-count response model for the high-dimensional drug combinatory effect on myopathy. Stat Med. 2018 Feb 20;37(4):673-686. doi: 10.1002/sim.7545. Epub 2017 Nov 23. PMID: 29171062 Free PMC article.

McDowell ML, Tonismae TR, Slaven JE, Abernathy MP, Shanks AL, Benjamin TD, Quinney SK. The Impact of Hepatitis C Virus Infection on Buprenorphine Dose in Pregnancy. Am J Perinatol. 2020 Jan;37(1):73-78. doi: 10.1055/s-0039-1698838. Epub 2019 Oct 26. PMID: 31655490

Quinney SK, Haehner BD, Rhoades MB, Lin Z, Gorski JC, Hall SD. Interaction between midazolam and clarithromycin in the elderly. Br J Clin Pharmacol. 2008 Jan;65(1):98-109. doi: 10.1111/j.1365-2125.2007.02970.x. Epub 2007 Jul 17. PMID: 17635500 Free PMC article. Clinical Trial.

Friedman AN, Considine RV, Quinney SK. Inquiry into the short- and long-term effects of Roux-en-Y gastric bypass on the glomerular filtration rate. Ren Fail. 2020 Nov;42(1):624-628. doi: 10.1080/0886022X.2020.1790389.PMID: 32654577 Free PMC article.

Wu HY, Karnik S, Subhadarshini A, Wang Z, Philips S, Han X, Chiang C, Liu L, Boustani M, Rocha LM, Quinney SK, Flockhart D, Li L. An integrated pharmacokinetics ontology and corpus for text mining.BMC Bioinformatics. 2013 Feb 1;14:35. doi: 10.1186/1471-2105-14-35.PMID: 23374886 Free PMC article.

Friedman AN, Moe S, Fadel WF, Inman M, Mattar SG, Shihabi Z, Quinney SK. Predicting the glomerular filtration rate in bariatric surgery patients. Am J Nephrol. 2014;39(1):8-15. doi: 10.1159/000357231. Epub 2013 Dec 19. PMID: 24356416 Free PMC article.

Wu HY, Lu D, Hyder M, Zhang S, Quinney SK, Desta Z, Li L. DrugMetab: An Integrated Machine Learning and Lexicon Mapping Named Entity Recognition Method for Drug Metabolite. CPT Pharmacometrics Syst Pharmacol. 2018 Nov;7(11):709-717. doi: 10.1002/psp4.12340. Epub 2018 Sep 29. PMID: 30033622 Free PMC article.

Chiang CW, Zhang P, Wang X, Wang L, Zhang S, Ning X, Shen L, Quinney SK, Li L. Translational High-Dimensional Drug Interaction Discovery and Validation Using Health Record Databases and Pharmacokinetics Models. Clin Pharmacol Ther. 2018 Feb;103(2):287-295. doi: 10.1002/cpt.914. Epub 2017 Dec 11. PMID: 29052226

Miao J, Jin Y, Marunde RL, Gorski CJ, Kim S, Quinney S, Radovich M, Li L, Hall SD. Association of genotypes of the CYP3A cluster with midazolam disposition in vivo. Pharmacogenomics J. 2009 Oct;9(5):319-26. doi: 10.1038/tpj.2009.21. Epub 2009 Jun 9. PMID: 19506580 Free PMC article.

Quinney SK, Malireddy SR, Vuppalanchi R, Hamman MA, Chalasani N, Gorski JC, Hall SD. Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin. Eur J Clin Pharmacol. 2013 Mar;69(3):439-48. doi: 10.1007/s00228-012-1339-x. Epub 2012 Jul 10. PMID: 22777148 Free PMC article. Clinical Trial.

Shuster DL, Shireman LM, Ma X, Shen DD, Flood Nichols SK, Ahmed MS, Clark S, Caritis S, Venkataramanan R, Haas DM, Quinney SK, Haneline LS, Tita AT, Manuck TA, Thummel KE, Morris Brown L, Ren Z, Brown Z, Easterling TR, Hebert MF. Pharmacodynamics of Metformin in Pregnant Women With Gestational Diabetes Mellitus and Nonpregnant Women With Type 2 Diabetes Mellitus. J Clin Pharmacol. 2020 Apr;60(4):540-549. doi: 10.1002/jcph.1549. Epub 2019 Nov 19. PMID: 31742716 Free PMC article. Clinical Trial.

Oblak AL, Cope ZA, Quinney SK, Pandey RS, Biesdorf C, Masters AR, Onos KD, Haynes L, Keezer KJ, Meyer JA, Peters JS, Persohn SA, Bedwell AA, Eldridge K, Speedy R, Little G, Williams SP, Noarbe B, Obenaus A, Sasner M, Howell GR, Carter GW, Williams H, Lamb BT, Territo PR, Sukoff Rizzo SJ. Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice. Alzheimers Dement (N Y). 2022 Jul 14;8(1):e12317. doi: 10.1002/trc2.12317. eCollection 2022. PMID: 35846156 Free PMC article.

Dorr ML, Pierson RC, Daggy J, Quinney SK, Haas DM. Buccal versus Vaginal Misoprostol for Term Induction of Labor: A Retrospective Cohort Study. Am J Perinatol. 2019 Jun;36(7):765-772. doi: 10.1055/s-0038-1675219. Epub 2018 Oct 31. PMID: 30380580 Free PMC article.

Podichetty JT, Brinda BJ, Nelson RP, Karr AH, Prasad NK, Quinney S, Foxworthy Scott S, Kiel PJ. Pharmacokinetics of Basiliximab for the Prevention of Graft-versus-Host Disease in Patients Undergoing Hematopoietic Cell Transplantation with Minimal-Intensity Cyclophosphamide and Fludarabine. Pharmacotherapy. 2020 Jan;40(1):26-32. doi: 10.1002/phar.2347. Epub 2019 Dec 20. PMID: 31742732 Clinical Trial.

Quinney SK. Opportunities and Challenges of Using Big Data to Detect Drug-Drug Interaction Risk. Clin Pharmacol Ther. 2019 Jul;106(1):72-74. doi: 10.1002/cpt.1481. Epub 2019 Jun 11. PMID: 31184772 Free PMC article. No abstract available.

Haas DM, Daggy J, Flannery KM, Dorr ML, Bonsack C, Bhamidipalli SS, Pierson RC, Lathrop A, Towns R, Ngo N, Head A, Morgan S, Quinney SK. A comparison of vaginal versus buccal misoprostol for cervical ripening in women for labor induction at term (the IMPROVE trial): a triple-masked randomized controlled trial. Am J Obstet Gynecol. 2019 Sep;221(3):259.e1-259.e16. doi: 10.1016/j.ajog.2019.04.037. Epub 2019 May 7. PMID: 31075246 Free PMC article. Clinical Trial.

Zhang X, Galinsky RE, Kimura RE, Quinney SK, Jones DR, Hall SD. Inhibition of CYP3A by erythromycin: in vitro-in vivo correlation in rats. Drug Metab Dispos. 2010 Jan;38(1):61-72. doi: 0.1124/dmd.109.028290. PMID: 19797607

Haas DM, Quinney SK, Clay JM, Renbarger JL, Hebert MF, Clark S, Umans JG, Caritis SN; Obstetric-Fetal Pharmacology Research Units Network. Nifedipine pharmacokinetics are influenced by CYP3A5 genotype when used as a preterm labor tocolytic. Am J Perinatol. 2013 Apr;30(4):275-81. doi: 10.1055/s-0032-1323590. Epub 2012 Aug 8. PMID: 22875663 Free PMC article.

Quinney SK, Zhang X, Lucksiri A, Gorski JC, Li L, Hall SD. Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin. Drug Metab Dispos. 2010 Feb;38(2):241-8. doi: 10.1124/dmd.109.028746. Epub 2009 Nov 2. PMID: 19884323 Free PMC article.

Silva LL, Silvola RM, Haas DM, Quinney SK. Physiologically based pharmacokinetic modelling in pregnancy: Model reproducibility and external validation. Br J Clin Pharmacol. 2022 Feb;88(4):1441-1451. doi: 10.1111/bcp.15018. Epub 2021 Aug 26. PMID: 34337764

Blue EK, Ballman K, Boyle F, Oh E, Kono T, Quinney SK, Thurmond DC, Evans-Molina C, Haneline LS. Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats. Pediatr Res. 2015 Feb;77(2):316-25. doi: 10.1038/pr.2014.185. Epub 2014 Nov 20. PMID: 25412163 Free PMC article.

Zhang P, Li M, Chiang CW, Wang L, Xiang Y, Cheng L, Feng W, Schleyer TK, Quinney SK, Wu HY, Zeng D, Li L. Three-Component Mixture Model-Based Adverse Drug Event Signal Detection for the Adverse Event Reporting System. CPT Pharmacometrics Syst Pharmacol. 2018 Aug;7(8):499-506. doi:0.1002/psp4.12294. Epub 2018 Aug 9. PMID: 30091855 Free PMC article.

Zhang X, Quinney SK, Gorski JC, Jones DR, Hall SD. Semiphysiologically based pharmacokinetic models for the inhibition of midazolam clearance by diltiazem and its major metabolite. Drug Metab Dispos. 2009 Aug;37(8):1587-97. doi: 10.1124/dmd.109.026658. Epub 2009 May 6. PMID: 19420129 Clinical Trial.

Friedman AN, Strother M, Quinney SK, Hall S, Perkins SM, Brizendine EJ, Inman M, Gomez G, Shihabi Z, Moe S, Li L. Measuring the glomerular filtration rate in obese individuals without overt kidney disease. Nephron Clin Pract. 2010;116(3):c224-34. doi: 10.1159/000317203. Epub 2010 Jul 2. PMID: 20606483 Free PMC article. Clinical Trial.

Binkheder S, Wu HY, Quinney SK, Zhang S, Zitu MM, Chiang CW, Wang L, Jones J, Li L. PhenoDEF: a corpus for annotating sentences with information of phenotype definitions in biomedical literature. J Biomed Semantics. 2022 Jun 11;13(1):17. doi: 10.1186/s13326-022-00272-6. PMID: 35690873 Free PMC article.

Sanghani SP, Quinney SK, Fredenburg TB, Davis WI, Murry DJ, Bosron WF. Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3. Drug Metab Dispos. 2004 May;32(5):505-11. doi: 10.1124/dmd.32.5.505. PMID: 15100172

Towns R, Quinney SK, Pierson RC, Haas DM. Survey of Provider Preferences Regarding the Route of Misoprostol for Induction of Labor at Term. AJP Rep. 2017 Jul;7(3):e158-e162. doi: 10.1055/s-0037-1603954. Epub 2017 Jul 25. PMID: 28752015 Free PMC article.

Duke JD, Han X, Wang Z, Subhadarshini A, Karnik SD, Li X, Hall SD, Jin Y, Callaghan JT, Overhage MJ, Flockhart DA, Strother RM, Quinney SK, Li L. Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions. PLoS Comput Biol. 2012;8(8):e1002614. doi: 10.1371/journal.pcbi.1002614. Epub 2012 Aug 9. PMID: 22912565 Free PMC article.

Han X, Quinney SK, Wang Z, Zhang P, Duke J, Desta Z, Elmendorf JS, Flockhart DA, Li L. Identification and Mechanistic Investigation of Drug-Drug Interactions Associated With Myopathy: A Translational Approach. Clin Pharmacol Ther. 2015 Sep;98(3):321-7. doi: 10.1002/cpt.150. PMID: 25975815 Free PMC article.

Friedman AN, Quinney SK, Inman M, Mattar SG, Shihabi Z, Moe S. Influence of dietary protein on glomerular filtration before and after bariatric surgery: a cohort study. Am J Kidney Dis. 2014 Apr;63(4):598-603. doi: 10.1053/j.ajkd.2013.11.012. Epub 2013 Dec 31. PMID: 24387796 Free PMC article.

Friedman AN, Yu Z, Juliar BE, Nguyen JT, Strother M, Quinney SK, Li L, Inman M, Gomez G, Shihabi Z, Moe S. Independent influence of dietary protein on markers of kidney function and disease in obesity. Kidney Int. 2010 Oct;78(7):693-7. doi: 10.1038/ki.2010.184. Epub 2010 Jul 21. PMID: 20664561 Clinical Trial.

Blue EK, DiGiuseppe R, Derr-Yellin E, Acosta JC, Pay SL, Hanenberg H, Schellinger MM, Quinney SK, Mund JA, Case J, Haneline LS. Gestational diabetes induces alterations in the function of neonatal endothelial colony-forming cells. Pediatr Res. 2014 Feb;75(2):266-72. doi: 10.1038/pr.2013.224. Epub 2013 Nov 14. PMID: 24232636 Free PMC article.

Ferrari Gianlupi J, Mapder T, Sego TJ, Sluka JP, Quinney SK, Craig M, Stratford RE Jr, Glazier JA. Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2. Viruses. 2022 Mar 14;14(3):605. doi: 10.3390/v14030605. PMID: 35337012 Free PMC article.

Vorontsova Y, Haas DM, Flannery K, Masters AR, Silva LL, Pierson RC, Yeley B, Hogg G, Guise D, Heathman M, Quinney SK. Pharmacokinetics of vaginal versus buccal misoprostol for labor induction at term. Clin Transl Sci. 2022 May 19. doi: 10.1111/cts.13306. Online ahead of print. PMID: 35587540

Sanghani SP, Quinney SK, Fredenburg TB, Sun Z, Davis WI, Murry DJ, Cummings OW, Seitz DE, Bosron WF. Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. Clin Cancer Res. 2003 Oct 15;9(13):4983-91. PMID: 14581373

Du L, Chakraborty A, Chiang CW, Cheng L, Quinney SK, Wu H, Zhang P, Li L, Shen L. Graphic Mining of High-Order Drug Interactions and Their Directional Effects on Myopathy Using Electronic Medical Records. CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):481-8. doi: 10.1002/psp4.59. Epub 2015 Jul 6. PMID: 26380157 Free PMC article.

Egbelakin A, Ferguson MJ, MacGill EA, Lehmann AS, Topletz AR, Quinney SK, Li L, McCammack KC, Hall SD, Renbarger JL. Increased risk of vincristine neurotoxicity associated with low CYP3A5 expression genotype in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2011 Mar;56(3):361-7. doi: 10.1002/pbc.22845. Epub 2010 Nov 11. PMID: 21225912 Free PMC article.

Haas DM, Quinney SK, McCormick CL, Jones DR, Renbarger JL. A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic. J Matern Fetal Neonatal Med. 2012 Apr;25(4):419-23. doi: 10.3109/14767058.2011.583700. Epub 2011 Jun 7. PMID: 21644845 Clinical Trial.

Quinney SK, Galinsky RE, Jiyamapa-Serna VA, Chen Y, Hamman MA, Hall SD, Kimura RE. Hydroxyitraconazole, formed during intestinal first-pass metabolism of itraconazole, controls the time course of hepatic CYP3A inhibition and the bioavailability of itraconazole in rats. Drug Metab Dispos. 2008 Jun;36(6):1097-101. doi: 10.1124/dmd.108.020644. Epub 2008 Mar 13. PMID: 18339815

Wang L, Chiang C, Liang H, Wu H, Feng W, Quinney SK, Li J, Li L. How to Choose In Vitro Systems to Predict In Vivo Drug Clearance: A System Pharmacology Perspective. Biomed Res Int. 2015;2015:857327. doi: 10.1155/2015/857327. Epub 2015 Oct 11. PMID: 26539530 Free PMC article.

Wang Z, Kim S, Quinney SK, Guo Y, Hall SD, Rocha LM, Li L. Literature mining on pharmacokinetics numerical data: a feasibility study. J Biomed Inform. 2009 Aug;42(4):726-35. doi: 10.1016/j.jbi.2009.03.010. Epub 2009 Apr 2. PMID: 19345282 Free PMC article.

Quinney SK, Knopp S, Chang C, Hall SD, Li L. Integration of in vitro binding mechanism into the semiphysiologically based pharmacokinetic interaction model between ketoconazole and midazolam. CPT Pharmacometrics Syst Pharmacol. 2013 Sep 11;2(9):e75. doi: 10.1038/psp.2013.50. PMID: 24448021 Free PMC article.

Xu C, Quinney SK, Guo Y, Hall SD, Li L, Desta Z. CYP2B6 pharmacogenetics-based in vitro-in vivo extrapolation of efavirenz clearance by physiologically based pharmacokinetic modeling. Drug Metab Dispos. 2013 Dec;41(12):2004-11. doi: 10.1124/dmd.113.051755. Epub 2013 Jul 11. PMID: 23846872 Free PMC article. Clinical Trial.

Zhang P, Du L, Wang L, Liu M, Cheng L, Chiang CW, Wu HY, Quinney SK, Shen L, Li L. A Mixture Dose-Response Model for Identifying High-Dimensional Drug Interaction Effects on Myopathy Using Electronic Medical Record Databases. CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):474-80. doi: 10.1002/psp4.53. Epub 2015 Jul 6. PMID: 26380156 Free PMC article.

Quinney SK, Mohamed AN, Hebert MF, Haas DM, Clark S, Umans JG, Caritis SN, Li L. A Semi-Mechanistic Metabolism Model of CYP3A Substrates in Pregnancy: Predicting Changes in Midazolam and Nifedipine Pharmacokinetics. CPT Pharmacometrics Syst Pharmacol. 2012 Sep 26;1(9):e2. doi: 10.1038/psp.2012.5. PMID: 23835882 Free PMC article.

Nader AM, Quinney SK, Fadda HM, Foster DR. Effect of Gastric Fluid Volume on the In Vitro Dissolution and In Vivo Absorption of BCS Class II Drugs: a Case Study with Nifedipine. AAPS J. 2016 Jul;18(4):981-8. doi: 10.1208/s12248-016-9918-x. Epub 2016 Apr 22. PMID: 27106837 Free PMC article.

Wang Z, Kim S, Quinney SK, Zhou J, Li L. Non-compartment model to compartment model pharmacokinetics transformation meta-analysis--a multivariate nonlinear mixed model. BMC Syst Biol. 2010 May 28;4 Suppl 1(Suppl 1):S8. doi: 10.1186/1752-0509-4-S1-S8. PMID: 20522258 Free PMC article.

Osteen SJ, Yang Z, Mckinzie AH, Teal E, Tepper RS, Rhoads E, Quinney SK, Haneline LS, Haas DM. Long-term childhood outcomes for babies born at term who were exposed to antenatal corticosteroids. Am J Obstet Gynecol. 2022 Jul 21:S0002-9378(22)00580-4. doi: 10.1016/j.ajog.2022.07.026. Online ahead of print. PMID: 35872037

Binkheder S, Wu HY, Quinney SK, Zhang S, Zitu MM, Chiang CW, Wang L, Jones J, Li L. Correction: PhenoDEF: a corpus for annotating sentences with information of phenotype definitions in biomedical literature. J Biomed Semantics. 2022 Jul 20;13(1):20. doi: 10.1186/s13326-022-00275-3. PMID: 35858945 Free PMC article. No abstract available.

 

Anthony Raviele, PharmD*
Calkins H, Hindricks G, Cappato R, Kim YH, Saad EB, Aguinaga L, Akar JG, Badhwar V, Brugada J, Camm J, Chen PS, Chen SA, Chung MK, Cosedis Nielsen J, Curtis AB, Davies DW, Day JD, d'Avila A, Natasja de Groot NMS, Di Biase L, Duytschaever M, Edgerton JR, Ellenbogen KA, Ellinor PT, Ernst S, Fenelon G, Gerstenfeld EP, Haines DE, Haissaguerre M, Helm RH, Hylek E, Jackman WM, Jalife J, Kalman JM, Kautzner J, Kottkamp H, Kuck KH, Kumagai K, Lee R, Lewalter T, Lindsay BD, Macle L, Mansour M, Marchlinski FE, Michaud GF, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds MR, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao HM, Verma A, Wilber DJ, Yamane T; Document Reviewers:. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Europace. 2018 Jan 1;20(1):e1-e160. doi: 10.1093/europace/eux274. PMID: 29016840; PMCID: PMC5834122.
 
Collins KS, Raviele ALJ, Elchynski AL, Woodcock AM, Zhao Y, Cooper-DeHoff RM, Eadon MT. Genotype-Guided Hydralazine Therapy. Am J Nephrol. 2020;51(10):764-776. doi: 10.1159/000510433. Epub 2020 Sep 14. PMID: 32927458; PMCID: PMC7606720.

Jason Robarge, PhD*
Eadon MT, Desta Z, Levy KD, Decker BS, Pierson RC, Pratt VM, Callaghan JT, Rosenman MB, Carpenter JS, Holmes AM, McDonald CA, Benson EA, Patil AS, Vuppalanchi R, Gufford BT, Dave N, Robarge JD, Hyder MA, Haas DM, Kreutz RP, Dexter PR, Skaar TC, Flockhart DA. Implementation of a pharmacogenomics consult service to support the INGENIOUS trial. Clin Pharmacol Ther. 2016 Jul;100(1):63-6. doi: 10.1002/cpt.347. Epub 2016 Mar 31. PMID: 26850569; PMCID: PMC4899152.
 
Gufford BT, Robarge JD, Eadon MT, Gao H, Lin H, Liu Y, Desta Z, Skaar TC. Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes. Pharmacol Res Perspect. 2018 Mar 26;6(2):e00386. doi: 10.1002/prp2.386. PMID: 29610665; PMCID: PMC5869567.
 
Robarge JD, Metzger IF, Lu J, Thong N, Skaar TC, Desta Z, Bies RR. Population Pharmacokinetic Modeling To Estimate the Contributions of Genetic and Nongenetic Factors to Efavirenz Disposition. Antimicrob Agents Chemother. 2016 Dec 27;61(1):e01813-16. doi: 10.1128/AAC.01813-16. PMID: 27799204; PMCID: PMC5192152.
 
Schneider BP, Radovich M, Sledge GW, Robarge JD, Li L, Storniolo AM, Lemler S, Nguyen AT, Hancock BA, Stout M, Skaar T, Flockhart DA. Association of polymorphisms of angiogenesis genes with breast cancer. Breast Cancer Res Treat. 2008 Sep;111(1):157-63. doi: 10.1007/s10549-007-9755-9. Epub 2007 Sep 20. PMID: 17891484.
 
Schneider BP, Radovich M, Flockhart DA, Carpenter JS, Li L, Robarge JD, Storniolo AM, Hancock BA, Skaar TC, Sledge GW. Exploratory study evaluating the association of polymorphisms of angiogenesis genes with hot flashes. Breast Cancer Res Treat. 2009 Aug;116(3):543-9. doi: 10.1007/s10549-008-0178-z. Epub 2008 Sep 11. PMID: 18785001.
 
Robarge JD, Desta Z, Nguyen AT, Li L, Hertz D, Rae JM, Hayes DF, Storniolo AM, Stearns V, Flockhart DA, Skaar TC, Henry NL. Effects of exemestane and letrozole therapy on plasma concentrations of estrogens in a randomized trial of postmenopausal women with breast cancer. Breast Cancer Res Treat. 2017 Feb;161(3):453-461. doi: 10.1007/s10549-016-4077-4. Epub 2016 Dec 9. PMID: 27943008; PMCID: PMC5429096.
 
Borges S, Desta Z, Jin Y, Faouzi A, Robarge JD, Philips S, Nguyen A, Stearns V, Hayes D, Rae JM, Skaar TC, Flockhart DA, Li L. Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients. J Clin Pharmacol. 2010 Apr;50(4):450-8. doi: 10.1177/0091270009359182. Epub 2010 Jan 15. Erratum in: J Clin Pharmacol. 2010 Jun;50(6):725. Philip, Santosh [corrected to Philips, Sanosh]. PMID: 20081063; PMCID: PMC3816977.
 
Jin Y, Hayes DF, Li L, Robarge JD, Skaar TC, Philips S, Nguyen A, Schott A, Hayden J, Lemler S, Storniolo AM, Flockhart DA, Stearns V. Estrogen receptor genotypes influence hot flash prevalence and composite score before and after tamoxifen therapy. J Clin Oncol. 2008 Dec 20;26(36):5849-54. doi: 10.1200/JCO.2008.16.8377. Epub 2008 Nov 17. PMID: 19018086; PMCID: PMC2645113.
 
Abdelhady AM, Shugg T, Thong N, Lu JB, Kreutz Y, Jaynes HA, Robarge JD, Tisdale JE, Desta Z, Overholser BR. Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele Carriers. J Cardiovasc Electrophysiol. 2016 Oct;27(10):1206-1213. doi: 10.1111/jce.13032. Epub 2016 Jul 25. PMID: 27333947; PMCID: PMC5065384.
 
Robarge JD, Li L, Desta Z, Nguyen A, Flockhart DA. The star-allele nomenclature: retooling for translational genomics. Clin Pharmacol Ther. 2007 Sep;82(3):244-8. doi: 10.1038/sj.clpt.6100284. PMID: 17700589.
 
Robarge JD, Duarte DB, Shariati B, Wang R, Flockhart DA, Vasko MR. Aromatase inhibitors augment nociceptive behaviors in rats and enhance the excitability of sensory neurons. Exp Neurol. 2016 Jul;281:53-65. doi: 10.1016/j.expneurol.2016.04.006. Epub 2016 Apr 9. PMID: 27072527; PMCID: PMC4877294.

Elizabeth Rowe, PhD
Tuteja S, Salloum RG, Elchynski AL, Smith DM, Rowe E, Blake KV, Limdi NA, Aquilante CL, Bates J, Beitelshees AL, Cipriani A, Duong BQ, Empey PE, Formea CM, Hicks JK, Mroz P, Oslin D, Pasternak AL, Petry N, Ramsey LB, Schlichte A, Swain SM, Ward KM, Wiisanen K, Skaar TC, Van Driest SL, Cavallari LH, Bishop JR; IGNITE Pharmacogenetics Working Group. Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy. Clin Transl Sci. 2022 Feb;15(2):371-383. doi: 10.1111/cts.13154. Epub 2021 Sep 25. PMID: 34562070; PMCID: PMC8841452.
 
Shugg T, Ly RC, Rowe EJ, Philips S, Hyder MA, Radovich M, Rosenman MB, Pratt VM, Callaghan JT, Desta Z, Schneider BP, Skaar TC. Clinical Opportunities for Germline Pharmacogenetics and Management of Drug-Drug Interactions in Patients With Advanced Solid Cancers. JCO Precis Oncol. 2022 Feb;6:e2100312. doi: 10.1200/PO.21.00312. PMID: 35201852.
 
Salloum RG, Bishop JR, Elchynski AL, Smith DM, Rowe E, Blake KV, Limdi NA, Aquilante CL, Bates J, Beitelshees AL, Cipriani A, Duong BQ, Empey PE, Formea CM, Hicks JK, Mroz P, Oslin D, Pasternak AL, Petry N, Ramsey LB, Schlichte A, Swain SM, Ward KM, Wiisanen K, Skaar TC, Van Driest SL, Cavallari LH, Tuteja S. Best-worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy. Implement Sci Commun. 2022 May 14;3(1):52. doi: 10.1186/s43058-022-00300-7. PMID: 35568931; PMCID: PMC9107643.

Tyler Shugg, PharmD, PhD
Ly RC, Shugg T, Ratcliff R, Osei W, Lynnes TC, Pratt VM, Schneider BP, Radovich M, Bray SM, Salisbury BA, Parikh B, Sahinalp SC, Numanagić I, Skaar TC. Analytical Validation of a Computational Method for Pharmacogenetic Genotyping from Clinical Whole Exome Sequencing. J Mol Diagn. 2022 Jun;24(6):576-585. doi: 10.1016/j.jmoldx.2022.03.008. Epub 2022 Apr 20. PMID: 35452844; PMCID: PMC9227988.
 
Shugg T, Ly RC, Rowe EJ, Philips S, Hyder MA, Radovich M, Rosenman MB, Pratt VM, Callaghan JT, Desta Z, Schneider BP, Skaar TC. Clinical Opportunities for Germline Pharmacogenetics and Management of Drug-Drug Interactions in Patients With Advanced Solid Cancers. JCO Precis Oncol. 2022 Feb;6:e2100312. doi: 10.1200/PO.21.00312. PMID: 35201852.
 
Powell NR, Shugg T, Ly RC, Albany C, Radovich M, Schneider BP, Skaar TC. Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report. Front Oncol. 2022 Jan 31;11:809527. doi: 10.3389/fonc.2021.809527. PMID: 35174070; PMCID: PMC8841796.
 
Shugg T, Pasternak AL, Luzum JA. Comparison of clinical pharmacogenetic recommendations across therapeutic areas. Pharmacogenet Genomics. 2022 Feb 1;32(2):51-59. doi: 10.1097/FPC.0000000000000452. PMID: 34412102; PMCID: PMC8702450.
 
Shugg T, Pasternak AL, London B, Luzum JA. Prevalence and types of inconsistencies in clinical pharmacogenetic recommendations among major U.S. sources. NPJ Genom Med. 2020 Oct 30;5:48. doi: 10.1038/s41525-020-00156-7. PMID: 33145028; PMCID: PMC7603298.
 
Shugg T, Dave N, Amarh E, Assiri AA, Pollok KE, Overholser BR. Letrozole targets the human ether-a-go-go-related gene potassium current in glioblastoma. Basic Clin Pharmacol Toxicol. 2021 Mar;128(3):357-365. doi: 10.1111/bcpt.13515. Epub 2020 Oct 27. PMID: 33040444; PMCID: PMC7889647.
 
Shugg T, Hudmon A, Overholser BR. Neurohormonal Regulation of IKs in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death. J Am Heart Assoc. 2020 Sep 15;9(18):e016900. doi: 10.1161/JAHA.120.016900. Epub 2020 Aug 31. PMID: 32865116; PMCID: PMC7726975.
 
Shugg T, Somberg JC, Molnar J, Overholser BR. Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol. JACC Clin Electrophysiol. 2020 Jul;6(7):756-759. doi: 10.1016/j.jacep.2020.05.037. PMID: 32703555.
 
Shugg T, Egly C, Stamatkin CW, Patil AS, Tisdale JE, Overholser BR. Progesterone Metabolites Inhibit the Human Ether-a-go-go-Related Gene and Predict QT Interval Length. J Clin Pharmacol. 2019 Dec 12. doi: 10.1002/jcph.1563. Epub ahead of print. PMID: 31829451.
 
Luzum JA, Ting C, Peterson EL, Gui H, Shugg T, Williams LK, Li L, Sadee W, Wang D, Lanfear DE. Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure. Cardiovasc Drugs Ther. 2019 Dec;33(6):693-700. doi: 10.1007/s10557-019-06909-6. PMID: 31728800; PMCID: PMC7197488.
 
Shugg T, Johnson DE, Shao M, Lai X, Witzmann F, Cummins TR, Rubart-Von-der Lohe M, Hudmon A, Overholser BR. Calcium/calmodulin-dependent protein kinase II regulation of IKs during sustained β-adrenergic receptor stimulation. Heart Rhythm. 2018 Jun;15(6):895-904. doi: 10.1016/j.hrthm.2018.01.024. Epub 2018 Feb 2. PMID: 29410121; PMCID: PMC5984714.
 
Abdelhady AM, Shugg T, Thong N, Lu JB, Kreutz Y, Jaynes HA, Robarge JD, Tisdale JE, Desta Z, Overholser BR. Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele Carriers. J Cardiovasc Electrophysiol. 2016 Oct;27(10):1206-1213. doi: 10.1111/jce.13032. Epub 2016 Jul 25. PMID: 27333947; PMCID: PMC5065384.
 
Xu P, Bajaj G, Shugg T, Van Alstine WG, Yeo Y. Zwitterionic chitosan derivatives for pH-sensitive stealth coating. Biomacromolecules. 2010 Sep 13;11(9):2352-8. doi: 10.1021/bm100481r. PMID: 20695636; PMCID: PMC2941802.

Larissa Silva, PharmD*
Kinney MT, Quinney SK, Trussell HK, Silva LL, Ibrahim SA, Haas DM. Do maternal demographics and prenatal history impact the efficacy of betamethasone therapy for threatened preterm labor? BMC Pregnancy Childbirth. 2021 Jun 24;21(1):442. doi: 10.1186/s12884-021-03949-5. PMID: 34167497; PMCID: PMC8228510.
 
Silva LL, Silvola RM, Haas DM, Quinney SK. Physiologically based pharmacokinetic modelling in pregnancy: Model reproducibility and external validation. Br J Clin Pharmacol. 2022 Feb;88(4):1441-1451. doi: 10.1111/bcp.15018. Epub 2021 Aug 26. PMID: 34337764.
 
Vorontsova Y, Haas DM, Flannery K, Masters AR, Silva LL, Pierson RC, Yeley B, Hogg G, Guise D, Heathman M, Quinney SK. Pharmacokinetics of vaginal versus buccal misoprostol for labor induction at term. Clin Transl Sci. 2022 May 19. doi: 10.1111/cts.13306. Epub ahead of print. PMID: 35587540.

Rebecca Silvola, PharmD*
Marks C, Silvola R, Teal E, Quinney SK, Haas DM. Comparing newborn outcomes after prenatal exposure to individual antidepressants: A retrospective cohort study. Pharmacotherapy. 2021 Nov;41(11):907-914. doi: 10.1002/phar.2628. Epub 2021 Oct 26. PMID: 34587291; PMCID: PMC8608752.
 
Podichetty JT, Silvola RM, Rodriguez-Romero V, Bergstrom RF, Vakilynejad M, Bies RR, Stratford RE Jr. Application of machine learning to predict reduction in total PANSS score and enrich enrollment in schizophrenia clinical trials. Clin Transl Sci. 2021 Sep;14(5):1864-1874. doi: 10.1111/cts.13035. Epub 2021 May 3. PMID: 33939284; PMCID: PMC8504834.
 
Silva LL, Silvola RM, Haas DM, Quinney SK. Physiologically based pharmacokinetic modelling in pregnancy: Model reproducibility and external validation. Br J Clin Pharmacol. 2022 Feb;88(4):1441-1451. doi: 10.1111/bcp.15018. Epub 2021 Aug 26. PMID: 34337764.

Matthew Strother, MD*
Busakhala NW, Waako PJ, Strother MR, Keter AK, Kigen GK, Asirwa FC, Loehrer PJ. Randomized Phase IIA Trial of Gemcitabine Compared With Bleomycin Plus Vincristine for Treatment of Kaposi's Sarcoma in Patients on Combination Antiretroviral Therapy in Western Kenya. J Glob Oncol. 2018 Sep;4:1-9. doi: 10.1200/JGO.17.00077. PMID: 30241150; PMCID: PMC6223418.
 
Khozaim K, Orang'o E, Christoffersen-Deb A, Itsura P, Oguda J, Muliro H, Ndiema J, Mwangi G, Strother M, Cu-Uvin S, Rosen B, Washington S. Successes and challenges of establishing a cervical cancer screening and treatment program in western Kenya. Int J Gynaecol Obstet. 2014 Jan;124(1):12-8. doi: 10.1016/j.ijgo.2013.06.035. Epub 2013 Sep 25. PMID: 24140218.
 
Friedman AN, Strother M, Quinney SK, Hall S, Perkins SM, Brizendine EJ, Inman M, Gomez G, Shihabi Z, Moe S, Li L. Measuring the glomerular filtration rate in obese individuals without overt kidney disease. Nephron Clin Pract. 2010;116(3):c224-34. doi: 10.1159/000317203. Epub 2010 Jul 2. PMID: 20606483; PMCID: PMC2945276.
 
Friedman AN, Yu Z, Juliar BE, Nguyen JT, Strother M, Quinney SK, Li L, Inman M, Gomez G, Shihabi Z, Moe S. Independent influence of dietary protein on markers of kidney function and disease in obesity. Kidney Int. 2010 Oct;78(7):693-7. doi: 10.1038/ki.2010.184. Epub 2010 Jul 21. PMID: 20664561.

Gerald So, PharmD*

No current publications.


Irin Tanaudommongkon, PharmD*

TBA.


David Thacker, PharmD*
Lima JJ, Thomas CD, Barbarino J, Desta Z, Van Driest SL, El Rouby N, Johnson JA, Cavallari LH, Shakhnovich V, Thacker DL, Scott SA, Schwab M, Uppugunduri CRS, Formea CM, Franciosi JP, Sangkuhl K, Gaedigk A, Klein TE, Gammal RS, Furuta T. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing. Clin Pharmacol Ther. 2021 Jun;109(6):1417-1423. doi: 10.1002/cpt.2015. Epub 2020 Sep 20. PMID: 32770672; PMCID: PMC7868475.
 
Thacker DL, Modak A, Flockhart DA, Desta Z. Is (+)-[13C]-pantoprazole better than (±)-[13C]-pantoprazole for the breath test to evaluate CYP2C19 enzyme activity? J Breath Res. 2013 Mar;7(1):016001. doi: 10.1088/1752-7155/7/1/016001. Epub 2012 Dec 21. PMID: 23257668; PMCID: PMC3587180.
 
Thacker DL, Modak A, Nguyen PD, Flockhart DA, Desta Z. Stereoselective pharmacokinetics of stable isotope (+/-)-[13C]-pantoprazole: Implications for a rapid screening phenotype test of CYP2C19 activity. Chirality. 2011 Nov;23(10):904-9. doi: 10.1002/chir.21011. Epub 2011 Sep 20. PMID: 21935988; PMCID: PMC4409653.

Michelle Torres, MD*

TBA.


Yana Voronstova, PharmD*
Vorontsova Y, Haas DM, Flannery K, Masters AR, Silva LL, Pierson RC, Yeley B, Hogg G, Guise D, Heathman M, Quinney SK. Pharmacokinetics of vaginal versus buccal misoprostol for labor induction at term. Clin Transl Sci. 2022 May 19. doi: 10.1111/cts.13306. Epub ahead of print. PMID: 35587540.

Blessed Winston, MD
Umukoro NN, Aruldhas BW, Rossos R, Pawale D, Renschler JS, Sadhasivam S. Pharmacogenomics of oxycodone: a narrative literature review. Pharmacogenomics. 2021;22(5):275-290. doi:10.2217/pgs-2020-0143
 
Packiasabapathy S, Aruldhas BW, Horn N, et al. Pharmacogenomics of methadone: a narrative review of the literature. Pharmacogenomics. 2020;21(12):871-887. doi:10.2217/pgs-2020-0040
 
Packiasabapathy S, Zhang X, Ding L, Aruldhas BW, Pawale D, Sadhasivam S. Quantitative Pupillometry as a Predictor of Pediatric Postoperative Opioid-Induced Respiratory Depression. Anesth Analg. 2021;133(4):991-999. doi:10.1213/ANE.0000000000005579
 
Aruldhas BW, Quinney SK, Overholser BR, et al. Pharmacokinetic modeling of R and S-Methadone and their metabolites to study the effects of various covariates in post-operative children. CPT Pharmacometrics Syst Pharmacol. 2021;10(10):1183-1194. doi:10.1002/psp4.12687
 
Packiasabapathy S, Aruldhas BW, Zhang P, Overholser BR, Quinney SK, Sadhasivam S. Novel associations between CYP2B6 polymorphisms, perioperative methadone metabolism and clinical outcomes in children. Pharmacogenomics. 2021;22(10):591-602. doi:10.2217/pgs-2021-0039
 
Sadhasivam S, Aruldhas BW, Packiasabapathy S, et al. A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects. Anesth Analg. 2021;133(2):327-337. doi:10.1213/ANE.0000000000005366