CPT Code(s): 81405
Ordering Recommendation: PSEN1 full gene sequencing is recommended for individuals with clinical symptoms of early onset Alzheimer disease, which begins before age 65, and individuals with a positive family history of early-onset Alzheimer disease.
Synonyms: PSEN1, Presenilin 1, Alzheimer disease, early onset Alzheimer disease, dementia
Methodology: Sanger sequence analysis. The PSEN1 cDNA reference sequence used is NM_000021.4.
Performed: Monday through Friday
Reported: 14 days