Jamie L. Renbarger, MD, MS
Associate Professor of Pediatrics
My career path has been driven by my passion for taking care of patients, developing relationships, and teaching. During my initial pediatric rotation as a third year medical student, I found that I loved caring for children because of their resiliency and innocence. I was also attracted to pediatrics because of the multitude of academic opportunities in the field. Early in my residency, I developed a passion for pediatric hematology/oncology as well as pediatric critical care, attracted by the medical and psychosocial intensities of both fields. Within pediatric hematology/oncology, I was particularly drawn to the clinical care of pediatric hematopoietic stem cell transplant patients and ultimately chose this over critical care due to the opportunity to develop long-term relationships with patients and their families who we have the privilege to see for many years. I embarked upon my pediatric hematology/oncology fellowship training at Baylor College of Medicine with an open mind and an interest in getting good research experience as a foundation for my future academic career. I have always enjoyed thinking about medications, their mechanisms of action, and variability in both response and side effects. As such I decided to join the cancer pharmacology group for my fellowship research. I became passionate about developing ways to predict response to specific therapies we use in children with cancer and, in particular, understanding inter-individual variability in responses and toxicities. My hope is that my passion and research will lead to a better understanding on how to best treat individual children with cancer where the ultimate, initial goal is disease cure rather than control of symptoms. I feel privileged to come to work and think about ways to improve our approaches to caring for our patients.
Titles & Appointments
- Caroline Symmes Scholar in Pediatric Cancer Research
- Associate Professor of Medicine
- Associate Professor of Obstetrics & Gynecology
My primary research interest as a pediatric oncologist/stem cell transplant physician is in personalized medicine and pharmacogenomics in the treatment of childhood cancers. Our work involves a major effort to identify biomarkers of drug toxicity and efficacy in the treatment of pediatric cancers. The ultimate goal is to use these biomarkers to develop simple, robust and practical clinical predictors of response to medications in individual patients that can be used to optimize dosing in the treatment of children, many of whom have curable malignancies. I have extensive clinical and translational research experience involving an investigation of biomarkers in a variety of pediatric populations. As a pediatrician trained in both pediatric hematology/oncology and clinical pharmacology, I also serve as Interim Director of the Indiana Institute for Personalized Medicine. I am the co-PI of the Indiana HSCT Biobank (co-PIs S. Paczesny and J. Renbarger), a longitudinal clinic-biologic repository of de-identified samples linked to relevant clinical information. I am also the principal investigator on the Indiana University Center for Pediatric Pharmacology and Precision Medicine (U54HD090215, 9/1/2016 – 8/31/2021), funded by NICHD. As evidence of my establishing IU as a leader in pediatric clinical pharmacology, with a specific focus on optimizing treatments for children with cancer, the Indiana Center for Pediatric Pharmacology was awarded funding from NICHD as one of four centers of excellence in the U.S. for research in pediatric and developmental pharmacology (U54 HD071598, 9/2011-6/2017). I am currently the PI for an NIH T32 postdoctoral training grant (T32 HD069047; Indiana Pediatric Pharmacology Training Program; 5/1/2011 – 4/31/2019) as well as the Recruiting Officer for the IU Pediatric K12 Award (K12 HD068371; PI Clapp, 2/2013-11/2018).
American Society of Clinical Oncology
American Academy of Pediatrics
American Society for Pediatric Hematology/Oncology
American Society for Clinical Pharmacology and Therapeutics
American Association for Cancer Research
American Board of Pediatrics - Pediatric Hematology-Oncology
Desc: Alpha Omega Alpha