Richard N. Day

Richard N. Day, PhD

Professor of Anatomy, Cell Biology & Physiology


Research in my laboratory applies quantitative fluorescence microscopy techniques to visualize the behaviors of proteins inside living cells.  Our studies use the combination of molecular biology, biochemistry, and live-cell imaging approaches to determine how specific signal transduction and gene regulatory complexes are assembled.  We are using time-resolved fluorescence lifetime imaging microscopy (FLIM) to measure Förster resonance energy transfer (FRET), which enables us to determine how certain disease-causing point mutations can affect the assembly of specific protein complexes.  I have over one hundred publications, with extensive experience in live-cell imaging.  In addition, I have taught in the annual Cold Spring Harbor Laboratory or Marine Biological Laboratory live-cell imaging courses yearly since 1998, and I am currently the co-organizer for the Workshop on FRET microscopy, held annually at the University of Virginia since 2001.


(317) 274-2166 

Cellular & Integrative Physiology
Indianapolis, IN