Jason M. Organ, PhD
Assistant Professor of Anatomy & Cell Biology
The Organ Lab at IUSM studies the relationship between bone and muscle mechanics at the whole-organ level, and how tissue-level mechanisms influence whole-organ function. We utilize numerous in vivo model systems to understand how disease, exercise, and pharmaceutical intervention influence bone and muscle structure, cellular activity, and biomechanical properties. We study these properties in the context of chronic kidney disease, osteogenesis imperfecta, and normal postnatal ontogeny, using a variety of techniques: imaging (CT, DXA, X-ray), histology (static and dynamic histomorphometry), muscle electrophysiology (in vivo ankle torque, in vitro whole muscle contractility), and bone mechanical testing (bending, compression, reference point indentation). The Organ Lab is funded by the NIH and IUSM/Showalter Research Trust.
American Society for Bone and Mineral Research
American Association of Anatomists