2003 FEL Harvard Medical School

2000 FEL Washington University in St. Louis

1997 PhD Chinese Academy of Sciences

1992 MMED Southern Medical University

1989 BMED Southern Medical University

Stem cell research offers unprecedented opportunities to explore fundamental questions of biology and to develop novel medical therapies for debilitating diseases such as injury, neurodegenerative diseases, and aging. The long-term goals of my laboratory are to explore the molecular and cellular mechanisms that regulate neurogenesis in the adult hippocampus and to seek the potential of stem cells for repairing neocortical circuitry damaged by traumatic brain injury. We are interested in understanding cellular and molecular mechanisms that are responsible for neural stem/progenitor cell fate determination and development of adult-born neurons in thenormal or injured brain. The 

The methods we use to pursue this goal include conditional knockout, primary culture, videomicroscopy (real-time imaging), confocal imaging, virology, histology, biochemistry, and molecular biology.

Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer.
Wu W; Wagner EK; Hao Y; Rao X; Dai H; Han J; Chen J; Storniolo AM; Liu Y; He C; Scientific reports 2016 Sep 6

Shifts in the fecal microbiota associated with adenomatous polyps.
Hale VL; Chen J; Johnson S; Harrington SC; Yab TC; Smyrk TC; Nelson H; Boardman LA; Druliner BR; Levin TR; Rex DK; Ahnen DJ; Lance P; Ahlquist DA; Chia N; Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2016 Sep 26

Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk.
Chen J; Varga A; Selvarajah S; Jenes A; Dienes B; Sousa-Valente J; Kulik A; Veress G; Brain SD; Baker D; Urban L; Mackie K; Nagy I; Scientific reports 2016 Sep 22

Protein Kinase Cd Suppresses Autophagy to Induce Kidney Cell Apoptosis in Cisplatin Nephrotoxicity.
Zhang D; Pan J; Xiang X; Liu Y; Dong G; Livingston MJ; Chen JK; Yin XM; Dong Z; Journal of the American Society of Nephrology : JASN 2016 Oct 31

Growth at Two Years of Age in HIV-Exposed Uninfected Children in the US by Trimester of Maternal Antiretroviral Initiation.
Jacobson DL; Patel K; Williams PL; Geffner ME; Siberry GK; Dimeglio LA; Crain MJ; Mirza A; Chen JS; McFarland E; Kacanek D; Silio M; Rich K; Borkowsky W; Van Dyke RB; Miller TL; Pediatric HIVAIDS Cohort Study.; The Pediatric infectious disease journal 2016 Oct 27

Compression-induced structural and mechanical changes of fibrin-collagen composites.
Kim OV; Litvinov RI; Chen J; Chen DZ; Weisel JW; Alber MS; Matrix biology : journal of the International Society for Matrix Biology 2016 Oct 15

HIV Tat Impairs Neurogenesis through Functioning As a Notch Ligand and Activation of Notch Signaling Pathway.
Fan Y; Gao X; Chen J; Liu Y; He JJ; The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Nov 2

Postnatal dysregulation of Notch signal disrupts dendrite development of adult-born neurons in the hippocampus and contributes to memory impairment.
Ding XF; Gao X; Ding XC; Fan M; Chen J; Scientific reports 2016 May 13

Beam Energy Dependence of the Third Harmonic of Azimuthal Correlations in Au+Au Collisions at RHIC.
Adamczyk L; Adkins JK; Agakishiev G; Aggarwal MM; Ahammed Z; Alekseev I; Aparin A; Arkhipkin D; Aschenauer EC; Attri A; Averichev GS; Bai X; Bairathi V; Bellwied R; Bhasin A; Bhati AK; Bhattarai P; Bielcik J; Bielcikova J; Bland LC; Bordyuzhin IG; Bouchet J; Brandenburg JD; Brandin AV; Bunzarov I; Butterworth J; Caines H; Calderón de la Barca Sánchez M; Campbell JM; Cebra D; Chakaberia I; Chaloupka P; Chang Z; Chatterjee A; Chattopadhyay S; Chen JH; Chen X; Cheng J; Cherney M; Christie W; Contin G; Crawford HJ; Das S; De Silva LC; Debbe RR; Dedovich TG; Deng J; Derevschikov AA; di Ruzza B; Didenko L; Dilks C; Dong X; Drachenberg JL; Draper JE; Du CM; Dunkelberger LE; Dunlop JC; Efimov LG; Engelage J; Eppley G; Esha R; Evdokimov O; Eyser O; Fatemi R; Fazio S; Federic P; Fedorisin J; Feng Z; Filip P; Fisyak Y; Flores CE; Fulek L; Gagliardi CA; Garand D; Geurts F; Gibson A; Girard M; Greiner L; Grosnick D; Gunarathne DS; Guo Y; Gupta S; Gupta A; Guryn W; Hamad AI; Hamed A; Haque R; Harris JW; He L; Heppelmann S; Heppelmann S; Hirsch A; Hoffmann GW; Horvat S; Huang T; Huang X; Huang B; Huang HZ; Huck P; Humanic TJ; Igo G; Jacobs WW; Jang H; Jentsch A; Jia J; Jiang K; Judd EG; Kabana S; Kalinkin D; Kang K; Kauder K; Ke HW; Keane D; Kechechyan A; Khan ZH; Kikola DP; Kisel I; Kisiel A; Kochenda L; Koetke DD; Kosarzewski LK; Kraishan AF; Kravtsov P; Krueger K; Kumar L; Lamont MA; Landgraf JM; Landry KD; Lauret J; Lebedev A; Lednicky R; Lee JH; Li X; Li C; Li X; Li Y; Li W; Lin T; Lisa MA; Liu F; Ljubicic T; Llope WJ; Lomnitz M; Longacre RS; Luo X; Ma R; Ma GL; Ma YG; Ma L; Magdy N; Majka R; Manion A; Margetis S; Markert C; Matis HS; McDonald D; McKinzie S; Meehan K; Mei JC; Minaev NG; Mioduszewski S; Mishra D; Mohanty B; Mondal MM; Morozov DA; Mustafa MK; Nandi BK; Nasim M; Nayak TK; Nigmatkulov G; Niida T; Nogach LV; Noh SY; Novak J; Nurushev SB; Odyniec G; Ogawa A; Oh K; Okorokov VA; Olvitt D; Page BS; Pak R; Pan YX; Pandit Y; Panebratsev Y; Pawlik B; Pei H; Perkins C; Pi Physical review letters 2016 Mar 18

Observation of h_{c} Radiative Decay h_{c}???^{'} and Evidence for h_{c}???.
Ablikim M; Achasov MN; Ai XC; Albayrak O; Albrecht M; Ambrose DJ; Amoroso A; An FF; An Q; Bai JZ; Baldini Ferroli R; Ban Y; Bennett DW; Bennett JV; Bertani M; Bettoni D; Bian JM; Bianchi F; Boger E; Boyko I; Briere RA; Cai H; Cai X; Cakir O; Calcaterra A; Cao GF; Cetin SA; Chang JF; Chelkov G; Chen G; Chen HS; Chen HY; Chen JC; Chen ML; Chen S; Chen SJ; Chen X; Chen XR; Chen YB; Cheng HP; Chu XK; Cibinetto G; Dai HL; Dai JP; Dbeyssi A; Dedovich D; Deng ZY; Denig A; Denysenko I; Destefanis M; De Mori F; Ding Y; Dong C; Dong J; Dong LY; Dong MY; Dou ZL; Du SX; Duan PF; Fan JZ; Fang J; Fang SS; Fang X; Fang Y; Farinelli R; Fava L; Fedorov O; Feldbauer F; Felici G; Feng CQ; Fioravanti E; Fritsch M; Fu CD; Gao Q; Gao XL; Gao XY; Gao Y; Gao Z; Garzia I; Goetzen K; Gong L; Gong WX; Gradl W; Greco M; Gu MH; Gu YT; Guan YH; Guo AQ; Guo LB; Guo RP; Guo Y; Guo YP; Haddadi Z; Hafner A; Han S; Hao XQ; Harris FA; He KL; Held T; Heng YK; Hou ZL; Hu C; Hu HM; Hu JF; Hu T; Hu Y; Huang GS; Huang JS; Huang XT; Huang XZ; Huang Y; Huang ZL; Hussain T; Ji Q; Ji QP; Ji XB; Ji XL; Jiang LW; Jiang XS; Jiang XY; Jiao JB; Jiao Z; Jin DP; Jin S; Johansson T; Julin A; Kalantar-Nayestanaki N; Kang XL; Kang XS; Kavatsyuk M; Ke BC; Kiese P; Kliemt R; Kloss B; Kolcu OB; Kopf B; Kornicer M; Kupsc A; Kühn W; Lange JS; Lara M; Larin P; Leng C; Li C; Li C; Li DM; Li F; Li FY; Li G; Li HB; Li HJ; Li JC; Li J; Li K; Li K; Li L; Li PR; Li QY; Li T; Li WD; Li WG; Li XL; Li XN; Li XQ; Li YB; Li ZB; Liang H; Liang YF; Liang YT; Liao GR; Lin DX; Liu B; Liu BJ; Liu CX; Liu D; Liu FH; Liu F; Liu F; Liu HB; Liu HH; Liu HH; Liu HM; Liu J; Liu JB; Liu JP; Liu JY; Liu K; Liu KY; Liu LD; Liu PL; Liu Q; Liu SB; Liu X; Liu YB; Liu ZA; Liu Z; Loehner H; Lou XC; Lu HJ; Lu JG; Lu Y; Lu YP; Luo CL; Luo MX; Luo T; Luo XL; Lyu XR; Ma FC; Ma HL; Ma LL; Ma MM; Ma QM; Ma T; Ma XN; Ma XY; Ma YM; Maas FE; Maggiora M; Mao YJ; Mao ZP; Marcello S; Messchendorp JG; Min J; Mitchell RE; Mo XH; Mo YJ; Morales Morales C; Muchnoi NY; Mur Physical review letters 2016 Jun 21

Kinetic Transition Networks for the Thomson Problem and Smale's Seventh Problem.
Mehta D; Chen J; Chen DZ; Kusumaatmaja H; Wales DJ; Physical review letters 2016 Jul 6

Observation of an Anomalous Line Shape of the ?^{'}p^{+}p^{-} Mass Spectrum near the pp[over ¯] Mass Threshold in J/????^{'}p^{+}p^{-}.
Ablikim M; Achasov MN; Ahmed S; Ai XC; Albayrak O; Albrecht M; Ambrose DJ; Amoroso A; An FF; An Q; Bai JZ; Baldini Ferroli R; Ban Y; Bennett DW; Bennett JV; Berger N; Bertani M; Bettoni D; Bian JM; Bianchi F; Boger E; Boyko I; Briere RA; Cai H; Cai X; Cakir O; Calcaterra A; Cao GF; Cetin SA; Chang JF; Chelkov G; Chen G; Chen HS; Chen HY; Chen JC; Chen ML; Chen S; Chen SJ; Chen X; Chen XR; Chen YB; Cheng HP; Chu XK; Cibinetto G; Dai HL; Dai JP; Dbeyssi A; Dedovich D; Deng ZY; Denig A; Denysenko I; Destefanis M; De Mori F; Ding Y; Dong C; Dong J; Dong LY; Dong MY; Dou ZL; Du SX; Duan PF; Fan JZ; Fang J; Fang SS; Fang X; Fang Y; Farinelli R; Fava L; Fedorov O; Feldbauer F; Felici G; Feng CQ; Fioravanti E; Fritsch M; Fu CD; Gao Q; Gao XL; Gao XY; Gao Y; Gao Z; Garzia I; Goetzen K; Gong L; Gong WX; Gradl W; Greco M; Gu MH; Gu YT; Guan YH; Guo AQ; Guo LB; Guo RP; Guo Y; Guo YP; Haddadi Z; Hafner A; Han S; Hao XQ; Harris FA; He KL; Heinsius FH; Held T; Heng YK; Holtmann T; Hou ZL; Hu C; Hu HM; Hu JF; Hu T; Hu Y; Huang GS; Huang YP; Huang JS; Huang XT; Huang XZ; Huang Y; Huang ZL; Hussain T; Ji Q; Ji QP; Ji XB; Ji XL; Jiang LW; Jiang XS; Jiang XY; Jiao JB; Jiao Z; Jin DP; Jin S; Johansson T; Julin A; Kalantar-Nayestanaki N; Kang XL; Kang XS; Kavatsyuk M; Ke BC; Kiese P; Kliemt R; Kloss B; Kolcu OB; Kopf B; Kornicer M; Kupsc A; Kühn W; Lange JS; Lara M; Larin P; Leithoff H; Leng C; Li C; Li C; Li DM; Li F; Li FY; Li G; Li HB; Li HJ; Li JC; Li J; Li K; Li K; Li L; Li PR; Li QY; Li T; Li WD; Li WG; Li XL; Li XN; Li XQ; Li YB; Li ZB; Liang H; Liang YF; Liang YT; Liao GR; Lin DX; Liu B; Liu BJ; Liu CX; Liu D; Liu FH; Liu F; Liu F; Liu HB; Liu HH; Liu HH; Liu HM; Liu J; Liu JB; Liu JP; Liu JY; Liu K; Liu KY; Liu LD; Liu PL; Liu Q; Liu SB; Liu X; Liu YB; Liu YY; Liu ZA; Liu Z; Loehner H; Lou XC; Lu HJ; Lu JG; Lu Y; Lu YP; Luo CL; Luo MX; Luo T; Luo XL; Lyu XR; Ma FC; Ma HL; Ma LL; Ma MM; Ma QM; Ma T; Ma XN; Ma XY; Ma YM; Maas FE; Maggiora M; Malik QA; Mao YJ; Mao ZP; Marcello S; M Physical review letters 2016 Jul 21

Temporal Purity and Quantum Interference of Single Photons from Two Independent Cold Atomic Ensembles.
Qian P; Gu Z; Cao R; Wen R; Ou ZY; Chen JF; Zhang W; Physical review letters 2016 Jul 1

A method for identifying discriminative isoform-specific peptides for clinical proteomics application.
Zhang F; Chen JY; BMC genomics 2016 Aug 22

Treatment patterns in patients with advanced gastric cancer in Taiwan.
Cuyun Carter G; Kaltenboeck A; Ivanova J; Liepa AM; San Roman A; Koh M; Rajan N; Cheng R; Birnbaum H; Chen JS; Asia-Pacific journal of clinical oncology 2016 Apr 25

Measurement of the Transverse Single-Spin Asymmetry in p^{?}+p?W^{±}/Z^{0} at RHIC.
Adamczyk L; Adkins JK; Agakishiev G; Aggarwal MM; Ahammed Z; Alekseev I; Aparin A; Arkhipkin D; Aschenauer EC; Attri A; Averichev GS; Bai X; Bairathi V; Banerjee A; Bellwied R; Bhasin A; Bhati AK; Bhattarai P; Bielcik J; Bielcikova J; Bland LC; Bordyuzhin IG; Bouchet J; Brandenburg JD; Brandin AV; Bunzarov I; Butterworth J; Caines H; Calderón de la Barca Sánchez M; Campbell JM; Cebra D; Chakaberia I; Chaloupka P; Chang Z; Chattopadhyay S; Chen X; Chen JH; Cheng J; Cherney M; Christie W; Contin G; Crawford HJ; Das S; De Silva LC; Debbe RR; Dedovich TG; Deng J; Derevschikov AA; di Ruzza B; Didenko L; Dilks C; Dong X; Drachenberg JL; Draper JE; Du CM; Dunkelberger LE; Dunlop JC; Efimov LG; Engelage J; Eppley G; Esha R; Evdokimov O; Eyser O; Fatemi R; Fazio S; Federic P; Fedorisin J; Feng Z; Filip P; Fisyak Y; Flores CE; Fulek L; Gagliardi CA; Garand D; Geurts F; Gibson A; Girard M; Greiner L; Grosnick D; Gunarathne DS; Guo Y; Gupta A; Gupta S; Guryn W; Hamad A; Hamed A; Haque R; Harris JW; He L; Heppelmann S; Heppelmann S; Hirsch A; Hoffmann GW; Hofman DJ; Horvat S; Huang X; Huang HZ; Huang B; Huang T; Huck P; Humanic TJ; Igo G; Jacobs WW; Jang H; Jentsch A; Jia J; Jiang K; Judd EG; Kabana S; Kalinkin D; Kang K; Kauder K; Ke HW; Keane D; Kechechyan A; Khan ZH; Kikola DP; Kisel I; Kisiel A; Kochenda L; Koetke DD; Kosarzewski LK; Kraishan AF; Kravtsov P; Krueger K; Kumar L; Lamont MA; Landgraf JM; Landry KD; Lauret J; Lebedev A; Lednicky R; Lee JH; Li C; Li Y; Li W; Li X; Li X; Lin T; Lisa MA; Liu F; Ljubicic T; Llope WJ; Lomnitz M; Longacre RS; Luo X; Ma R; Ma L; Ma GL; Ma YG; Magdy N; Majka R; Manion A; Margetis S; Markert C; McDonald D; Meehan K; Mei JC; Minaev NG; Mioduszewski S; Mishra D; Mohanty B; Mondal MM; Morozov DA; Mustafa MK; Nandi BK; Nasim M; Nayak TK; Nigmatkulov G; Niida T; Nogach LV; Noh SY; Novak J; Nurushev SB; Odyniec G; Ogawa A; Oh K; Okorokov VA; Olvitt D; Page BS; Pak R; Pan YX; Pandit Y; Panebratsev Y; Pawlik B; Pei H; Perkins C; Pile P; Pluta J; Physical review letters 2016 Apr 1