Richard L. Bell, MD, PhD
Associate Professor of Psychiatry
My research is focused on understanding alcohol use and dependence in order to develop pharmacotherapies to treat these disorders. As the Director of the “Animal Production Core (APC)”, within the Indiana Alcohol Research Center (IARC), and a U24 “Rodents with Genetic Differences in Alcohol Preference“ I oversee the selective breeding of the alcohol-preferring P and nonpreferring NP as well as the replicate high alcohol drinking vs low alcohol drinking HAD1/LAD1 and HAD2/LAD2 rat lines. These mechanisms, through the National Institute on Alcohol Abuse and Alcoholism, provide these selectively bred rats to investigators locally and around the world. The P/NP as well as HAD1/LAD1 and HAD2/LAD2 rats are excellent genetic animal models for studying factors influencing the development of alcoholism, such as changes in (1) reward neurocircuitry; (2) the relationship of temperament-like behavior to alcohol preference; (3) binge drinking during peri-adolescence and its long-term consequences; (4) ‘relapse’ or ‘out-of-control’ drinking (alcohol deprivation effect); (5) functional (CNS) alcohol tolerance, and alcohol dependence; as well as (6) co-abuse of alcohol and other substances of abuse. I also am active in educating preclinical researchers and clinical practitioners on alcoholism, its underlying neurobiology, as well as the promises and pitfalls of developing pharmacotherapies to treat this disorder.
NB 300C, Neuroscience Research Bldg.
The neurobiology of alcohol and other drug use disorders. The behavioral and pharmacological genetics of addiction. Preclinical testing of novel, as well as repurposing, compounds to treat substance use disorders.
International Society for Biomedical Research on Alcoholism
Research Society on Alcoholism
Society for Neuroscience