Jill C. Fehrenbacher

Jill C. Fehrenbacher, PhD

Assistant Professor of Pharmacology & Toxicology





Maria Yeung Dental Research Award

University of Texas Health Science Center

San Antonio, Texas



Dental Science Symposiumn

1st Place, Postdoctoral Division

University of Texas Health Science Center

San Antonio, Texas



Center for Biomedical Neuroscience 

Annual Retreat

First Place Postdoctoral Division


2004 - 2005

K.K. Chen Fellowship

Indiana University School of Medicine

Indianapolis, Indiana



Graduate Student Educational Enhancement Award

Indiana University Graduate School

Indianapolis, Indiana


1995 - 1999

Scholastic Excellence Award

University of Southern Indiana

Evansville, Indiana


1998 - 1999

Bertram Bennett Athletic and Academic Excellence Scholarship

University of  Southern Indiana

Evansville, Indiana


Key Publications

Darby LM, Meng H, Fehrenbacher JC (2017). Paclitaxel inhibits the activity and membrane localization of PKCα and PKCβI/II to elicit a decrease in stimulated calcitonin gene-related peptide release from cultured sensory neurons, Molecular and Cellular Neuroscience, 82: 105.

Shah F, Logsdon D, Messman R, Fehrenbacher JC, Fishel M, Kelley M (2017). Exploiting the APE1-Ref-1 node in cancer signaling and other diseases: from bench to clinic. Nature Partner Journals Precision Oncology, 1: Article #19.

Fehrenbacher JC and Richardson JD (2017).  NSAIDs and Acetaminophen. Brody's Human Pharmacology: Mechanism-Based Therapeutics, 6th edition, in press.

Kelley M, Fehrenbacher JC (2017). Challenges and opportunities identifying therapeutic targets for chemotherapy-induced peripheral neuropathy resulting from oxidative DNA damage. Neural Regeneration Research, 12:72.

Malty RH, Hudmon A, Fehrenbacher JC, Vasko MR. (2016) Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. J Neuroinflammation 11:181.

Pittman SP, Gracias N, Fehrenbacher JC. (2016) Nerve growth factor alters microtubule targeting agent-induced neurotransmitter release but not MTA-induced neurite retraction in sensory neurons. Experimental Neurology, 279:104-115.

Duarte DB, Vasko MR, Fehrenbacher JC (2016). Models of Inflammation: Carrageenan Air Pouch. Current Protocols in Pharmacology, 72:5.6.1-9

Fehrenbacher JC, Bingener J, Aho JM, Wasky PR, Locke EE, Schwesinger WH, Van Sickle KR, Hargreaves KM (2015). Men with acute cholecystitis have higher tissue-based cytokine levels than women: a cross-sectional study. Chirurgia, 28:49-53.

Fehrenbacher JC (2015). Chemotherapy-induced peripheral neuropathy. Prog Mol Biol Tranl Sci: 131:471.

Chen X, Sun W, Glanaris NG, Riley AM, Cummins TR, Fehrenbacher JC, Obukhov AG (2014). Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel. J Biol Chem: 289: 9600.

Pittman SP, Gracias N, Vasko MR, Fehrenbacher JC (2014). Paclitaxel alters the evoked release of calcitonin gene-related peptide from rat sensory neurons in culture. Experimental Neurology: 253: 146.

Fehrenbacher JC, Vasko MR, Duarte DB (2012). Models of Inflammation: Carrageenan- or Complete Freund’s Adjuvant-Induced Edema and Hypersensitivity in the Rat. Current Protocols in Pharmacology, 5: Unit 5.4.

Duarte DB, Vasko MR, Fehrenbacher JC (2012). Models of Inflammation: Carrageenan Air Pouch. Current Protocols in Pharmacology, 5: Unit 5.6.


Brittain JM, Duarte DB, Wilson SM, Wang Y, Zhu W, Ballard C, Khanna M, Brustovetsky T, Schmutzler BS, Xiong W, Ripsch MS, Ashpole NM, Hudmon A, Meroueh SO, Hingtgen CM, Brustovesky N, Jim X, Vasko MR, Fehrenbacher JC, Hurley JH, White FA, Khanna R. (2011) Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex. Nature Medicine; 17:822.


Park KA, Fehrenbacher JC, Thompson EL, Guo CL, Hingtgen CM, Vasko MR. (2010) Nerve Growth Factor Augments Expression of Calcitonin Gene-Related Peptide in Sensory Neurons through activation of the Ras Signaling Cascade. Neuroscience; 171:910.


Fehrenbacher JC, Sun XX, Locke EE, Henry M, Hargreaves KM. (2009) Capsaicin-evoked iCGRP release from human dental pulp: a model system for the study of peripheral neuropeptide secretion in normal healthy tissue. Pain, 144:253-61.


Fehrenbacher JC, LoVerme J, Clarke W, Hargreaves KM, Piomelli D, Taylor BK. (2009) Rapid Pain Modulation with Nuclear Receptor Ligands. Brain Res Rev, 60:114-24.


Jeske NA, Diogenes A, Ruparel NB, Fehrenbacher JC, Henry M, Akopian AN, Hargreaves KM. (2008) A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1. Pain, 138: 604-16.


Zhang Y, Fehrenbacher JC, Vasko MR, Nicol GD. (2006) Sphingosine-1-phosphate via activation of a G protein-coupled receptor(s) enhances the excitability of rat sensory neurons. J Neurophys, 96: 1042-52.


Patwardhan AM, Diogenes A, Akopian AN, Berg KA, Clarke WP, Fehrenbacher JC, Hargreaves KM. (2006). PAR-2 agonists activate trigeminal nociceptors and induce functional competence in the Delta opioid receptor. Pain, 125: 114-24.


Fehrenbacher JC, Burkey TH, Nicol GD and Vasko MR. (2005). Tumor necrosis factor alpha and interleukin-1beta stimulate the expression of cyclooxygenase II but do not alter prostaglandin E2 receptor mRNA levels in cultured dorsal root ganglia cells. Pain, 113: 113-22.


Fehrenbacher JC, Taylor CP, Vasko MR. (2003). Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C.  Pain, 105: 133-41.



(317) 274-8360 

Pharmacology & Toxicology
Indianapolis, IN