Tune Lab

The research lab of Johnathan D. Tune, PhD, focuses on the regulation of coronary blood flow, contractile function and metabolism in health and disease.

Active Research

Research in the Tune Lab focuses on the regulation of coronary blood flow, contractile function and metabolism in health and disease. The laboratory has been continuously funded for more than 15 years by the National Institutes of Health, the American Heart Association and the American Diabetes Association as well as pharmaceutical companies to elucidate mechanisms of impaired coronary and cardiac function in the setting of obesity and diabetes. The lab’s studies routinely include a series of experimental approaches utilizing both in vivo (chronically instrumented conscious and/or acute open-chest swine) and in vitro (isolated artery rings, pressurized arterioles, Western blot, RT-PCR, immunohistochemistry, confocal microscopy) methodologies to examine hypotheses in a highly integrative manner. These studies have led to more than 95 peer-reviewed publications and the successful training of numerous post-doctoral fellows, PhD and MS students.

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To stay current on the medical research work at IU School of Medicine, follow the IU School of Medicine research blog, where investigators throughout the school’s academic departments statewide post updates about their work.

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Recent Publications

A full list of Tune’s publication history is available on PubMed. Access to full length versions of publication can be found on Tune Research Gate.

Faculty Research Team

Matthew C. Aalsma, PhD, HSPP

Professor of Pediatrics

Eva B. Aamodt, MSC

Adjunct Lecturer in Neurology

Vasantha D. Aaron, MD

Assistant Professor of Clinical Radiology & Imaging Sciences

Joshua M. Aaron, MD

Adjunct Clinical Assistant Professor of Surgery

Abdul Rahman Aasar, MD

Diagnostic Radiology, PGY 3
Indiana University School of Medicine

Dilawer H. Abbas, MD

Adjunct Clinical Assistant Professor of Neurology

Mohammad Yaseen Abbasi, PharmD

Postdoctoral Fellow in Medicine

Nadeem Abbasi, MD, MBA

Adjunct Clinical Assistant Professor of Pediatrics

Rania K. Abbasi, MD

Associate Professor of Clinical Anesthesia

Additional Research Team Members

Other research team members in the Tune Lab include Joshua Sturek (Research Assistant).