Atwood Lab Publications and Funding

Munoz B, Haggerty DL, Atwood BK. Synapse-specific expression of mu opioid receptor long-term depression in the dorsomedial striatum. Scientific Reports. 10(1):7234 (2020).PMID: 32350330

Mulcahy G, Atwood B, Kuznetsov A. Basal Ganglia role in learning reward actions and executing previously learned choices: Healthy and diseased states. PLoS One. 2020 Feb 10;15(2):e0228081. PMID: 32040519

Haggerty DL, Grecco GG, Reeves K, Atwood BK. Adeno-associated viral vectors in neuroscience research. Molecular Therapy - Methods and Clinical Development. 17:69-82 (2019). PMID: 31890742

Fritz BM, Munoz B, Atwood BK. Genetic Selection for Alcohol Preference in Mice Alters Dorsal Striatum Neurotransmission. Alcoholism: Clinical and Experimental Research. 43 (11):2312-2321 (2019). PMID: 31491046.

Jay T, von Saucken VE, Muñoz B, Codocedo JF, Atwood BK, Lamb BT, Landreth GE. The neurodegeneration-associated receptor TREM2 is required for microglial instruction of astrocytic synaptic engulfment in neurodevelopment. Glia. 67(10):1873-1892 (2019). PMID: 31265185.

You Y, Perkins A, Cisternas P, Muñoz B, Taylor X, You Y, Garringer HJ, Oblak AL, Ghetti B, Atwood BK, Vidal R, Lasagna-Reeves C. Tau as a mediator of neurotoxicity associated to Cerebral Amyloid Angiopathy. Acta Neuropathologica Communications. 7(1):26 (2019). PMID: 30808415.

Munoz, B., Fritz, B.M., Yin, F., Atwood, B.K.  Alcohol exposure disrupts mu opioid receptor-mediated long-term depression at insular cortex inputs to dorsolateral striatum. Nature Communications. In press.

Fritz, B.M., Munoz, B., Yin, F., Bauchle, C., Atwood, B.K. A high-fat, high-sugar ‘western’ diet alters dorsal striatal glutamate, opioid, and dopamine transmission in mice. Neuroscience, Epub December 28, 2017. PMID: 29289718.

Mateo, Y., Johnson, K., Covery, D.P., Atwood, B.K., Wang, H.-L., Zhang, S., Gildish, I., Cachope, R., Bellocchio, L., Guzman, M., Morales, M., Cheer, J., Lovinger, D. M. Endocannabinoid Actions on Cortical Terminals Orchestrate Local Modulation of Dopamine Release in the Nucleus Accumbens. Neuron, 96(5):1112-1126 (2017). PMID: 29216450

Atwood, B.K., Lovinger, D.M. Endocannabinoid-Dependent Synaptic Plasticity in the Striatum. Endocannabinoids and Lipid Mediators in Brain Functions. 109-153 (2017)

Gremel, C., Chancey, J., Atwood, B.K., Luo, G., Neve, R., Ramakrishnan, C., Deisseroth, K., Lovinger, D.M., Costa, R. Endocannabinoid modulation of orbitostriatal circuits gates habit formation. Neuron. 90(6):1312-1324 (2016). PMID: 27238866

Atwood, B.K., Lovinger, D.M., Mathur, B.M. Presynaptic long-term depression mediated by Gi/o-coupled receptors. Trends in Neurosciences. 37(11): 663-673 (2014). PMID: 25160683

Atwood, B.K., Kupferschmidt, D.A., Lovinger, D.M. Opioids induce dissociable forms of long-term depression of excitatory inputs to the dorsal striatum. Nature Neuroscience. 17(4): 540-548 (2014). PMID: 24561996

Atwood, B.K., Wager-Miller, J., Haskins, C., Straiker, A, Mackie, K. Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands. Molecular Pharmacology. 81(2): 250-263 (2012). PMID: 22064678

Atwood, B.K., Straiker A., Mackie, K. CB(2) cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons. Neuropharmacology. 63(4): 514-523 (2012). PMID: 22579668

Atwood, B.K., Straiker, A., Mackie, K. CB(2): Therapeutic target-in-waiting. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 38(1): 16-20 (2012). PMID: 22197668

Atwood, B.K., Lopez, J., Wager-Miller, J., Mackie, K., Straiker, A. Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. BMC Genomics. 12:14. (2011). PMID: 21214938

Atwood, B.K., Lee, D., Straiker, A., Widlanski, T.S., Mackie, K. CP47,497-C8 and JWH073, commonly found in ‘Spice’ herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. European Journal of Pharmacology. 659(2-3): 139-145 (2011). PMID: 21333643

Atwood, B.K., Mackie, K. CB2: a cannabinoid receptor with an identity crisis. British Journal of Pharmacology. 160(3): 467-479 (2010). PMID: 20590558

Atwood, B.K., Huffman, J., Straiker, A., Mackie, K. JWH018, a common constituent of ‘Spice’ herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. British Journal of Pharmacology. 160(3): 585-593 (2010). PMID: 20100276

NIH/NIAAA        

09/01/19—08/31/20

Alzheimer’s Disease & Related Dementia Administrative Supplement for grant: Synapse-specific interactions between ethanol and opioid receptor-mediated synaptic depression in dorsal striatum

Role: PI

NIH/NIDA                                

04/15/18—3/31/21   

Spinophilin function in regulating pathological responses to psychostimulant drug

Role: Co-investigator

Indiana University

11/1/18-6/30/20        

Consequences of Opioid Neonatal Abstinence Syndrome

Role: Co-PI

NIH/NIAAA                 

9/26/18-5/25/21        

Project title: Dorsal Striatal Adenosine A1 Receptors in Alcohol-Induced Synaptic and Behavioral Plasticity

Role: F32 Mentor 

NIH/NIAAA                             

09/20/18-08/31/23                                   

Synapse-specific interactions between ethanol and opioid receptor-mediated synaptic depression in dorsal striatum

Role: PI

NIH/NIAAA                                                                 

Training Grant on Genetic Aspects of Alcoholism

Role: T32 Mentor for Graduate Students (Haggerty, Reeves)