Indiana University School of Medicine leads a comprehensive program in Alzheimer's disease research spanning basic, translational and clinical research, focused on optimizing clinical care for patients with Alzheimer's disease. The school, ranked No. 6 in the nation for National Institute of Aging research, received $87 million in National Institutes of Health grants to fund Alzheimer's disease research. From developing the next generation of animal models and testing potential therapeutics to working alongside clinical research participants and patients in the state's largest health system, IU School of Medicine has a rich research program and expertise widely recognized around the world.
Basic and Preclinical Science
Basic scientists research the neurobiology and molecular genetics of Alzheimer’s disease to define disease mechanisms using animal models, identify therapeutic targets, rigorously test drugs and create molecules for potential drugs.
Clinical and Translational Science
Researchers in clinical and translational science test new methods to diagnose, treat and prevent Alzheimer’s disease, and advancing this research into improved diagnosis and care for patients living with the disease.
Clinical Innovation
Researchers in clinical and translational science test new methods to diagnose, treat and prevent Alzheimer’s disease, and advancing this research into improved diagnosis and care for patients living with the disease.
Featured News
The findings highlight the major role inflammation plays in neurodegenerative disease progression.
November 07, 2025
Beyond the lab: Community liaisons contribute to breakthroughs in Alzheimer’s research at IU
As a community research liaison for the Department of Neurology, Zipporah Melton was determined to break down the multifaceted barriers that often prevent underrepresented communities from participating in clinical trails.November 03, 2025
Finding strength and support: The 19th annual Martin Family Alzheimer's Disease Caregivers Symposium
Caring for a loved one with Alzheimer's disease can be an incredibly tough journey, requiring great strength, resilience and a continuous quest for knowledge and support. The Martin Family Alzheimer's Disease Caregiver Symposium has been a beacon of hope and a vital resource for nearly twenty years for Hoosiers and many others.October 08, 2025
September 02, 2025
IU co-founded startup aims to propel novel Alzheimer’s disease drugs into clinical trials
The IU School of Medicine has several programs dedicated to Alzheimer's disease research, from basic and translational science to clinical research and innovation.
August 20, 2025
Candice Brown joined the IU School of Medicine to grow the school’s neurovascular basic science and clinical research programs.
August 14, 2025
From folding proteins to unfolding memories: An AI journey through Alzheimer's
This is the final column in a four-part series from Taeho Jo, assistant professor of radiology and imaging sciences at the IU School of Medicine, titled "AI in Medicine: From Nobel Discoveries to Clinical Frontiers."August 01, 2025
New national center at IU to develop stem cell brain models to better understand Alzheimer’s disease
Indiana University is leading the way nationally as the home to one of only two centers in the United States dedicated to developing stem-cell-based models of the human brain to better understand the underlying causes of Alzheimer's disease and dementias.
July 31, 2025
IU School of Medicine researchers receive top awards at international Alzheimer’s disease conference
Research leaders at the IU School of Medicine will receive two of the top six awards given out by the Alzheimer’s Association at its annual international conference.July 28, 2025