Dr. Chmiel was Associate Director, LeRoy W. Matthews Cystic Fibrosis Center, Division of Pediatric Pulmonology, Rainbow Babies and Children’s Hospital in Cleveland, Ohio, and Director of the Pediatric Pulmonology Fellowship at Case Western Reserve University (CWRU) for 14 years. Early in his career, Dr. Chmiel primarily focused in basic science and translational research to study the airway inflammatory response in a mouse model. He then transitioned to a clinical research career to better understand the inflammatory response of the lung, particularly as it relates to asthma and CF and the impact of anti-inflammatory therapeutics upon this response. Dr. Chmiel is particularly interested in studying the counter-regulatory mechanisms responsible for modulating the airway inflammatory response.
Dr. Chmiel participates in both independent and multi-center clinical trials and has been the lead PI on several multi-center studies sponsored by the Cystic Fibrosis Foundation’s Therapeutic Development Network (TDN). With more than fourteen years of experience mentoring various levels of academic trainees, Dr. Chmiel has mentored dozens of assistant or associate level professors, several of which have received NIH loan-repayment, early investigator Cystic Fibrosis Foundation or K awards.