Faculty in the Division of Pediatric Nephrology at IU School of Medicine participate in clinical, basic science, and translational studies locally and throughout the United States.

Clinical Research

The clinical research portfolio for pediatric nephrologists at IU School of Medicine includes studies for children with chronic kidney disease, glomerular disease, immunizations in children with kidney transplants or chronic kidney disease, novel therapies for nephrotic syndrome, children with complement disorders, and hypertension. The research portfolio also includes precision medicine in congenital anomalies of the kidney and urinary tract, urinary tract infections, intercalated cells and innate immunity, urinary stones, vaccinations in children with chronic kidney disease and transplant, and outcomes in kidney transplant patients. The Division of Pediatric Nephrology participates in multiple clinical trials, including Chronic Kidney Disease in Children (CKiD) and Cure Glomerulonephropathy (CureGN) studies.

Translational Research

With laboratories in the Herman B Wells Center for Pediatric Research, attached to Riley Hospital for Children, faculty in the Division of Pediatric Nephrology at IU School of Medicine benefit from the close proximity of the basic science labs to clinical studies. The team’s NIH-funded board-certified pediatric nephrologists use clinical questions to drive discoveries that will improve the care for children in the state of Indiana with kidney and urinary tract disease.

The Division’s robust translational science portfolio includes studies focused on improving how to care for children with kidney disease. Projects include genetic personalized medicine approaches for children with urinary tract infections, congenital anomalies of the kidney and urinary tract, and urinary stones. Additional research includes unique diagnostic projects for improving diagnosis of urinary tract infections, projects involving contrast enhanced ultrasound for children with reflux nephropathy and microbiome studies in children with urinary stone disease.