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IU Liver Research Group

The Liver Research group at Indiana University strongly believes that clinical research is vital to advance the understanding and treatment for various liver disorders. For instance, through clinical research, investigators gain insights and answers about the safety and effectiveness of drugs and other treatment interventions. Groundbreaking scientific advances in the present and the past were possible only because of active voluntary participation of patients and their families.

IU Liver Research faculty researchers work to help patients overcome barriers that prevent patients from taking part in clinical trials. These barriers may include lack of awareness, fear of side effects, assignment to placebo arm, confusion about insurance coverage and lastly time commitment and travel time to the research facility. Despite these barriers, the research program has had tremendous success over the years with recruitment and retention due to motivated patients who want to have access to new treatments and help advance science.

There have been several breakthroughs in the field of liver disease recently leading to several newer treatment options for liver disorders. These agents are currently under study through various phases of drug development. These phases include Phase 1 (dose finding study), Phase 2 (safety and preliminary efficacy) and Phase 3 (efficacy and safety). Completion of two (rarely one) studies with positive results is often required prior to approval by regulatory authorities.

A complete list of all diabetes clinical trials being conducted at IU School of Medicine can be found on the Indiana Clinical and Translational Sciences Institute (CTSI) website.

Related research units/resources

Faculty in this division is on the forefront of endoscopic research in the pancreaticobiliary tree and are recognized authorities on the application of ERCP to diseases of the pancreas and biliary tree.

The GI Motility Program at Indiana University Health is a regional referral center of excellence for GI Motility Disorders.

A repository of calculators specific to GI/Hepatology needs.

Publications

Liver Research Faculty are widely published in leading journals as a result of their work. More than 200 publications to date have been circulated and can be found through PubMed.