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Hiromi Tanaka, PhD
Assistant Professor of Medical & Molecular Genetics
Currently Dr. Tanaka's research studies mechanisms of genomic instability that cause tumorigenesis. The lab is developing innovative and quantitative assays for early cancer detection and measurement of chromosomal end-to-end fusions as a genetic biomarker. Chromosomal end-to-end fusion (or "telomere fusion") is a major hallmark of telomere dysfunction, which is likely a key driving force behind the genomic instability observed in early cancer lesions. Since genomic instability is one of the earliest neoplastic changes known to occur in tumorigenesis, determining its cause is critical for understanding the etiology of cancer for early detection and therapeutic purposes.