Biochemistry and Molecular Biology

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Biochemistry and Molecular Biology Research

Medical scientists working within the Department of Biochemistry and Molecular Biology at Indiana University School of Medicine put considerable focus on studying the biochemical and molecular basis of cancer, diabetes and obesity, neurological disorders, infectious diseases, cardiovascular malfunctions, and alcoholism—all areas of expertise of IU School of Medicine—and take pride in the extensive research collaborations that occur with the school’s other academic and clinical departments. Most of the faculty are associated with the Indiana Alcohol Research Center, Center for Diabetes and Metabolic Disease, Indiana University Simon Cancer Center and/ or other major research centers at IU School of Medicine.

Areas of faculty research include signal transduction mechanisms, molecular biology, enzyme catalysis, post-transcriptional control and post-translational modification, cell cycle and DNA repair, metabolic regulation, macromolecular structure and function, bioinformatics and computational biology, proteomics and genomics, gene regulation, chemical and structural biology, and high throughput methods for therapeutic discovery.

Research Facilities

Biochemistry and Molecular Biology faculty benefit from modern research facilities and advanced instrumentation—for microarrays and high-throughput genotyping, X-ray crystallography, chemical genomics, genome sequencing and molecular modeling—and are associated with one or more of the school’s major research centers, including the Indiana Alcohol Research Center, Center for Diabetes Research, Indiana University Simon Cancer Center and Center for Medical Genomics.

Research Service Support

Proteomics Core Lab

Proteomics Core Lab

The Proteomics Core at the Indiana University School of Medicine provides protein and proteomic analysis services for protein identification, characterization, and quantification. The Center encourages collaborations that apply the tools of proteomics to cutting-edge biomedical research.

Chemical Genomics Core Lab

Chemical Genomics Core Lab

The first core facility of its kind to be established in an academic setting in Indiana, the Chemical Genomic Core provides IU School of Medicine high-throughput screening and medicinal chemistry.

Service Cores

The IU School of Medicine Proteomics Core provides protein and proteomic analysis services for protein identification, characterization and quantification. The Center encourages collaborations that apply the tools of proteomics to biomedical research.

The Chemical Genomic Core provides Indiana University School of Medicine investigators high-throughput screening and medicinal chemistry and was the first core facility of its kind to be established in an academic setting in Indiana.

The Center for Medical Genomics provides affordable access to high-quality high-throughput genomics services for medical scientists studying gene expression and genetics.