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Renal Biology Research
Renal Biology research programs center on cell and molecular biology, pathology, biological imaging, and biophysics. Investigators are working to understand the cell- and tissue-level mechanisms involved in the development and treatment of chronic renal disease, with emphasis on polycystic kidney disease and nephrolithiasis. Current projects focus on epigenetic factors in the progression of PKD, pathogenesis of Meckel Syndrome, pathogenesis of tubulointerstitial fibrosis, Matrix Bone Disorder in chronic kidney disease, proteomics and biomarkers of human vascular calcification, pathogenesis of kidney stone formation, and bioeffects and mechanisms of shock-wave action in shock-wave lithotripsy.