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Sc2i-Woundx-001-Woundx Pilot Trial: Proof of Concept Feasibility for the Clinical Operations of Woundx in Aiding Clinicians Identify Wounds That Are Ready for Surgical Closure
The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experimental and ...
A Global Phase 3 Open-Label Extension Study to Assess the Long-Term Safety, Tolerability, and Efficacy of Intravenous AOC 1001 for the Treatment of Myotonic Dystrophy ...
To evaluate the long-term safety and tolerability of AOC 1001 in DM1 patients.THIS STUDY IS ENROLLING BY INVITATION ONLY - The study will invite participants with DM1 who completed ...
A Multicenter, Open-Label, Phase 1/2, Dose-Escalation and Subsequent Safety Extension Study of Subcutaneous KK8123 in Adult Patients with X-Linked Hypophosphatemia
The purpose of this study is to test the safety and effectiveness of an investigational drug called KK8123 in adults with X-linked hypophosphatemia. THIS STUDY IS ENROLLING BY INVITATION ONLY - ...
Cannulated Bone Bolt® Screw System Versus Standard Cannulated Screw System Fixation for Lateral Compression Type-1 Pelvic Ring Injuries: Multicenter Prospective Observational Study
The purpose of this study is to evaluate recovery and outcomes following cannulated Bone Bolt® screw system versus standard cannulated screw system fixation for LC-1 pelvic ring injuries. The devices ...
A Phase 3, Randomized, Double-Blind, 48-Week Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Dyne-101 Administered to Participants with Myotonic Dystrophy Type 1 ...
This Phase 3 study was designed based on the results of ACHIEVE. It is a randomized,double-blind study with a 48-week Placebo-Controlled Period to assess the efficacy, safety,and tolerability of DYNE-101 ...
Kysa-6: a Phase 2/3, Open-Label, Randomized, Controlled, Multicenter Study of Kyv-101, an Autologous Fully Human Anti-Cd19 Chimeric Antigen Receptor T-Cell (Cd19 Car T) Therapy, Versus ...
Myasthenia gravis (MG) is a chronic autoimmune disease that affects the neuromuscular junction and is characterized by muscle weakness. B cells play a role in MG, and the disease is ...
1010002807 a Study of Hematopoietic Stem Cell Transplantation (HSCT) in Non-Malignant Disease Using a Reduced-Intensity Preparatory Regime with Campath-1H Fludarabine and Melphalan
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is ...
1704113280 1704113280 1704113280 Prevention of Clot in Orthopaedic Trauma (PREVENT CLOT): a Randomized Pragmatic Trial Comparing the Complications and Safety of Blood Clot Prevention Medicines ...
The purpose of this research study is to help determine the best treatment for preventing blood clots that are formed following trauma that could potentially lead to death. At the ...
A Phase 2, Randomized, Human Growth Hormone-Controlled, Multicenter, Basket Study of Vosoritide in Children with Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome ...
The purpose of this study in children with Noonan syndrome is to evaluate the effect of 3 doses of vosoritide on growth as measured by AGV after 6 months of ...
A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety and Efficacy of Aga2115 in Adults with Type I, Iii, or Iv ...
This study will determine the effect of treatment of AGA2115 in adults with Type I, III, or IV osteogenesis imperfecta versus placebo