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Kysa-6: a Phase 2/3, Open-Label, Randomized, Controlled, Multicenter Study of Kyv-101, an Autologous Fully Human Anti-Cd19 Chimeric Antigen Receptor T-Cell (Cd19 Car T) Therapy, Versus ...
Myasthenia gravis (MG) is a chronic autoimmune disease that affects the neuromuscular junction and is characterized by muscle weakness. B cells play a role in MG, and the disease is ...
1011003357 in Vitro Expansion and Gene Transfer Using Peripheral Blood Stem Cells
The purpose of this study is to determine whether the quantity of peripheral blood stem cells can be made greater in the laboratory. Healthy male and female volunteer donors between ...
1403861741 1403861741 1403861741 Dissecting the Genetic and Environmental Contributions of Autoimmune Liver Disease: Genetic Repository of Autoimmune Liver Disease and Contributing Exposures (GRACE)Study
The overall objective of this proposal is to conduct a systematic approach to dissect both genetic underpinnings and non-genetic factors in the development of adult autoimmune liver diseases including autoimmune ...
A Phase 2 Study to Evaluate the Safety and Efficacy of Atacicept in Multiple Autoimmune Glomerular Diseases (PIONEER)
The purpose of this study is to evaluate the safety and tolerability of atacicept in adult and adolescent participants and to measure the effect in reducing proteinuria and preserving renal ...
A Phase 2B/3 Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Protocol to Evaluate the Efficacy and Safety of Icotrokinra in Participants with Moderately to Severely Active ...
The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in participants with moderately to severely active Crohn's disease (CD; a ...
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Dnth103 in Adults with Chronic Inflammatory Demyelinating Polyneuropathy (Captivate)
The purpose of this Phase 3 study is to demonstrate the efficacy of DNTH103 as compared to placebo in participants with chronic inflammatory demyelinating polyneuropathy (CIDP).THIS STUDY IS ENROLLING BY ...
A Phase III Multicenter Randomized, Double-Blind, Double-Dummy, Parallel-Group Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared with Teriflunomide in Adult Patients with Relapsing ...
A study to evaluate the efficacy and safety of fenebrutinib on disability progression and relapse rate in adult participants with RMS. Eligible participants will be randomized 1:1 to either fenebrutinib ...
A Multisite, Observational Study to Examine the Effects of Childhood-Onset SLE on Cognitive Functions Over Time, Using the Pedanam Tool for Cognitive and Behavioral Assessments ...
PRIMARY OBJECTIVES:The study's main objective is to track and analyze the long-term outcomes of neuropsychiatric systemic lupus erythematosus (NPSLE) in children and how it affects their cognitive functions over time. ...
Adalimumab Levels in Induction Control for Chronic Anterior Uveitis
?The purpose of this study is to understand whether blood levels of adalimumab (brand name: Humira) can be used to predict how well uveitis will respond to adalimumab. THIS STUDY IS ...
Autoimmune Liver Disease Network for Kids : Using Patient Data to Transform Care and Improve Outcomes for Children, Adolescents, and Young Adults with Autoimmune Liver ...
The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).This study will ...