Finding Immune Nascent Type 1 Diabetes (Find T1D) Pilot

ES

Emily Sims, MD

Principal Investigator

Status: Enrolling By Invitation Ages: 0 Years - 17 Years Gender: All Genders Phase: N/A 1 Locations

Brief Description

The purpose of this study is to understand how many individuals who previously participated in the Indiana Biobank will return a home screening kit. The participant will collect a capillary blood sample and hear about the results of testing that sample for markers of autoimmunity linked to type 1 diabetes.

THIS STUDY IS ENROLLING BY INVITATION ONLY - The Indiana Biobank will contact identified high-risk individuals by phone. Identified individuals will come from the top 5%-10% of individuals with high genetic risk and or those who are Ab positive from the Indiana Biobank protocol number 115005445. The Indiana Biobank personnel will ask potential participants about their interest in participating in our study. The Indiana Biobank will then provide our team with the names and contact information for those who are interested in our study. The diabetes research team will contact and consent those interested and will send a home collection capillary kit once consented.

Detailed Description

Individuals will be asked about interest in a research study related to type 1 diabetes based on prior participation in the Indiana Biobank. Interested individuals will be consented and the participant will be asked if we can use existing testing in Indiana Biobank samples with identifiers to understand if they have genetic markers signaling an increased risk for type 1 diabetes.

 The consented individuals will be sent a mail-based home screening kit.  Collected samples will be returned to the research team and tested for T1D autoantibodies. Results will be returned to participants and individuals with islet autoantibodies will be provided with the opportunity for follow-up counseling and testing, with referral for clinical follow-up as indicated.

Eligibility of study

Inclusion Criteria

1) Participant must have previously participated in Indiana Biobank
2) Participant must be able to provide consent

Exclusion Criteria

1) Refusal to sign informed consent 
2) Prior diabetes diagnosis

Interested in participating?

Enrollment in IU School of Medicine clinical trials is managed through our All IN for Health program. Many studies only accept people who are part of an invited group. Visit allinforhealth.info to connect with the study team, or contact your doctor to see if you are eligible.