Improving Sleep in Acute Respiratory Failure Survivors

BK

Babar Khan, MD

Principal Investigator

Status: Enrolling By Invitation Ages: 18 Years - 100 Years Gender: All Genders Phase: N/A 3 Locations

Brief Description

The purpose of this study is to evaluate the impact of a sleep deprivation and disruption on quality of life of acute respiratory failure ICU survivors using sleep actigraphy. Sleep actigraphy is a method of measuring sleep parameters and average motor activity over a period of days to weeks using a device worn on the wrist. The information provided can help characterize sleep patterns in this population, and guide future studies on treatment of sleep disorders after being discharged from intensive care.

Detailed Description

Participants will be asked to complete questionnaires about their sleep and have an actigraph placed on their wrist. Participants will be asked to return the actigraph after two weeks. Some participants will be asked to complete a sleep study in addition to wearing the actigraph.

Eligibility of study

Inclusion Criteria:
  • Hospitalized in the ICU
  • Diagnosed with Acute Respiratory Failure (ARF) requiring greater than or equal to 24 hours of mechanical ventilation
  • Discharged to home, skilled nursing facility, sub-acute rehabilitation care, or long-term acute care
  • English speaking
  • Able to consent either in-person or through legally authorized representative
  • Have access to a telephone
Exclusion Criteria:
  • Hospitalized to a regular non-ICU ward
  • Diagnosis of cancer with life expectancy less than 1 year
  • Admitted with ischemic or hemorrhagic cerebrovascular accident, traumatic brain injury, or undergoing neurosurgery
  • History of dementing illnesses and other neurodegenerative disease such as Alzheimer’s disease, Parkinson’s disease, or vascular dementia
  • Unable to complete study questionnaire due to severe hearing loss
  • Legally blind
  • Pregnant (assessed by urine pregnancy test) or nursing
  • Living outside the greater Indianapolis area
  • Recent history of alcohol or substance abuse
  • Status post tracheostomy and not eligible for a speaking valve
  • Incarcerated at the time of study enrollment

Interested in participating?

Enrollment in IU School of Medicine clinical trials is managed through our All IN for Health program. Many studies only accept people who are part of an invited group. Visit allinforhealth.info to connect with the study team, or contact your doctor to see if you are eligible.