Evaluating Different Methods of Circulating Tumor DNA Quantification in Oncology Patients

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Tim Lautenschlaeger, MD

Principal Investigator

Status: Enrolling By Invitation Ages: 18 Years - 100 Years Gender: All Genders Phase: N/A 5 Locations

Brief Description

What is the purpose of this study?
This study aims to invent a test that can see tiny pieces from people with cancer (specifically DNA from a person’s cancer) in blood and urine better than tests that can currently be done. In the future, this test can possibly be used to find a small cancer before other tests can find it. 

THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate clinical trial(s) at the time of their routine clinic visit. Occasionally, a patient may be a self-referral or physician referral, but are still screened for appropriate clinical trials at the time of their routine clinic visit. PI and staff may send copies of relevant consent forms to these patients to look over prior to actually consenting or enrolling them. This may take place at the patient's visit at which the consent is presented or the patient's next visit to the outpatient hematology/oncology clinic.

Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:
IU Clinical Trials Office 
Phone: (317) 278-5632

Detailed Description

What will happen during the study?
  • Participants will be asked to complete a 24 hour urine collection. Participants may be asked to complete a blood draw and some swab samples. Samples will be collected throughout the participant's cancer treatment journey. Researchers will ask permission to access participants' medical records for up to 10 years.

Eligibility of study

Inclusion Criteria:
  • Healthy individuals, patients with cancer, and patients with Hepatitis C
  • Cancer patients who plan to undergo therapy
  • Patients with Hepatitis C with a recent positive test
  • Ability to provide written informed consent and HIPAA authorization
Exclusion Criteria:
  • Dialysis dependent

Interested in participating?

Enrollment in IU School of Medicine clinical trials is managed through our All IN for Health program. Many studies only accept people who are part of an invited group. Visit allinforhealth.info to connect with the study team, or contact your doctor to see if you are eligible.