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Research Core Laboratories

Advanced Biomedical Information Technology - Bill Barnett, PhD, director 
Supercomputing, bioinformatics software, data management and database hosting, massive storage and advanced visualization services. 
Affiliations:  Indiana Genomics Initiative (INGEN), IU School of Medicine, University Information Technology Services (UITS) - Research Technologies Division


Cardiovascular Ischemia and Vasculogenesis (CIVC) — Brian Johnstone, PhD, director
Provides technical expertise and assistance in conducting experiments employing various rodent cardiovascular disease models for generating physiological data or for testing experimental compounds, molecules, cells or devices.
Affiliations: Center for Vascular Biology and Medicine, Department of Medicine, IU School of Medicine


Center for Medical Genomics — Howard Edenberg, PhD, director
Experimental design, infrastructure and consulting services for use of array-based technology in studies of disease and other biomedical research. Microsatellite and SNP genotyping, micro-array analysis of gene expression.
Affiliations: Alcohol Research Center, Department of Biochemistry and Molecular Biology, Indiana Genomics Initiative (INGEN), IU School of Medicine 


Chemical Genomics Core Facility — Zhong-Yin Zhang, PhD, director
Provides investigators with cost-effective access to high throughput screening of structurally-diverse, drug-like small molecules in biological assays to enable investigators to discover small molecule tools for basic research, therapeutic development and diagnostic applications.
Affiliations: Department of Biochemistry & Molecular Biology, IU School of Medicine


Clinical Pharmacology Analytical Core — David R. Jones, PhD, director
The Analytical Core provides services to 1) assist in the quantification of drugs and/or metabolites, 2) identification of metabolites, and 3) pharmacokinetic analysis of data.
Affiliations:   Department of Medicine – Clinical Pharmacology Division, IU Simon Cancer Center, IU School of Medicine


Computational Biology and Bioinformatics Service Core — Lang Li, PhD, director
This core, a service unit of the Center for Computational Biology and Bioinformatics, provides biomedical data management, informatic and analytical consulting, graphic and website design, and software and website hosting.
Affiliations:  Center for Computational Biology and Bioinformatics, Department of Biochemistry & Molecular Biology, IU School of Medicine


DNA Sequencing Core Facility - Robert A. Harris, PhD, director
DNA sequencing and quantitative PCR
Affiliations: IU Simon Cancer Center, IU School of Medicine


Electron Microscopy Center — Vincent Gattone, PhD, director
This core provides electron microscopy services utilizing either scanning or transmission electron microscopy.
Affiliations: Department of Anatomy & Cell Biology, IU School of Medicine


Flow Cytometry Resource Facility — Edward Srour, PhD, director
Cell sorting, immunofluorescence analysis and other flow cytometric assays.
Affiliations: IU Simon Cancer Center, IU School of Medicine


Indiana Center for Biological Microscopy — Kenneth Dunn, PhD, scientific director
High resolution confocal epifluorescence and multiphoton microscopy of cells, tissues and organs in living animals and fixed samples, and development of methods for imaging and digital image analysis.
Affiliations: Indiana Genomics Initiative (INGEN), IU Simon Cancer Center, IU School of Medicine


Indiana Center of Excellence in Biomedical Imaging — Gary D. Hutchins, PhD, director
Imaging of tissue biochemistry, physiology, and anatomy provided by the Indiana Center of Excellence in Biomedical Imaging.
Affiliations: Indiana Genomics Initiative (INGEN), IU School of Medicine


Proteomics Core Facility — Mu Wang, PhD, director
Identification, quantitation and characterization of proteins; instrumentation development.
Affiliations: Indiana Genomics Initiative (INGEN), Alcohol Research Center, INCAPS, IU School of Medicine


Transgenic & Knockout Mouse — Loren Field, PhD, director
Production of transgenic mouse lines using both blastocyst injection of embryonic stem cells and pronuclear injection of DNA.
Affiliations: Indiana Genomics Initiative (INGEN), IU Simon Cancer Center, IU School of Medicine


Translational Genomics Laboratory — Sunil Badve, MD, director
The Translational Genomics Laboratory provides services for 1) nucleic acid preparation, 2) genotyping, and 3) gene expression profiling.
Affiliations:  IU Simon Cancer Center, IU School of Medicine