Bio
Key Publications
Pederson, B.A. “Mammalian Glycogen Metabolism: Enzymology, Regulation, and Animal Models of Dysregulated Glycogen Metabolism”. Enzymology of Complex Alpha-glucans, edited by Felix Nitschke, CRC Press, 2021, pp. 83-136. Abstract
Pederson, B.A. (2019) “Structure and regulation of glycogen synthase in the brain.” Adv Neurobiol, 23: 83-123. Abstract
Chown, E.E., Wang, P., Zhao, X., Crowder, J.J., Strober, J.W., Sullivan, M.A., Xue, Y., Bennett, C.S.,Perri, A. M., Evers, B.M, Roach, P. J., Depaoli-Roach, A. A., Akman, H. O., Pederson, B. A., and Minassian, B.A (2020). "GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease." Ann Clin Transl Neurol. 7, 2186-2198. Abstract
Mayeuf-Louchart, A., Lancel, S., Sebti, Y., Pourcet, B., Loyens, A., Delhaye, S., Duhem,C., Beauchamp, J., Ferri, L., Thorel, Q., Boulinguiez, A., Zecchin, M., Dubois-Chevalier, J., Eeckhoute, J., Vaughn, L.T., Roach, P.J., Dani, C., Pederson, B.A., Vincent, S.D., Staels, B., and Duez, H. (2019) Glycogen dynamics drives lipid droplet biogenesis during brown adipocyte differentiation. Cell Reports 29, 1410-1418. Abstract
Pederson, B. A., Turnbull, J., Epp, J. R., Weaver, S. A., Zhao, X., Pencea, N., Roach, P. J., Frankland, P. W., Ackerley, C. A. and Minassian, B. A. (2013), Inhibiting glycogen synthesis prevents lafora disease in a mouse model. Annals of Neurology, 74: 297–300. Abstract | Full Text
Canada, S.E., Weaver, S.A., Sharpe, S.N, and Pederson, B.A. (2011) Brain glycogen supercompensation in the mouse after recovery from insulin-induced hypoglycemia. J. Neurosci. Res. 89, 585-591. Abstract | Full Text
Savage, D.B., Zhai, L., Ravikumar, B., Choi, C.S., Snaar, JEM., Medina-Gomez, G. Kim, S., McGuire, A.C., Wou, S-E., Bock, C.B., Evans, R.M., Vidal-Puig, A., Barroso, I., Shulman, G.U., Karpe, F., Taylor, R., Pederson, B.A., Roach, P.J., O'Rahilly, S., DePaoli-Roach, A.A. (2008) A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice. PLOS-Medicine. 5, e2. PMC2214798 | Abstract | Full Text | Supplementary Material | Correction
Pederson, B.A., Schroeder, J.M., Parker, G.E., Smith, M.W., Depaoli-Roach, A.A., Roach, P.J. (2005) Glucose metabolism in mice lacking muscle glycogen synthase. Diabetes ,54, 3466-3473. Abstract | Full Text
Pederson, B.A., Cope, C.R., Irimia, J.M., Schroeder, J.M., Thurberg, B.L., Depaoli-Roach, A.A., Roach, P.J. (2005) Mice with elevated muscle glycogen stores do not have improved exercise performance. Biochem. Biophys. Res. Commun. 331, 491-496. Abstract
Pederson, B.A., Cope, C.R., Schroeder, J.M., Smith, M.W., Irimia, J.M., Thurberg, B.L., Depaoli-Roach, A.A., Roach, P.J. (2005) Exercise capacity of mice genetically lacking muscle glycogen synthase: In mice, muscle glycogen is not essential for exercise. J. Biol. Chem. 280, 17260-17265. Abstract | Full Text | Full Text (PDF)
Pederson, B.A., Chen, H., Schroeder, J.M., Shou, W., Depaoli-Roach, A.A., Roach, P.J. (2004) Abnormal cardiac development in the absence of heart glycogen. Mol.Cell. Biol. 24, 7179-7187. Abstract | Full Text | Full Text (PDF)
Titles & Appointments
- Adjunct Associate Professor of Biochemistry & Molecular Biology
-
Education
-
Research